By Elisabeth Paymal Altogether, over 6,800 rare diseases affect an estimated 25 million to 30 million Americans. These patients who suffer from genetic mutations that often occur within the same family, are still nowadays left with few, if any, therapeutic options. However, RNA on-going discoveries and the development of new technology and tools such as…
KEYNOTE SPEAKER 5: March 26, 2021, 12:10–1:05 pm More information on the Symposium Blog by MiSciWriters “Mechanisms that target RNA for destruction” Christopher D. Lima, Ph.D. Alfred P. Sloan Chair; Chair and Member and Professor, Structural Biology Program, Sloan Kettering Institute; Investigator, Howard Hughes Medical Institute The Christopher Lima Lab TALK ABSTRACT Decay and…
KEYNOTE SPEAKER 3: March 25, 2021, 1:35–2:30 pm More information on the Symposium Blog by MiSciWriters “Exploration of Biological Diversity to Discover Novel Molecular Technologies” Feng Zhang, Ph.D. James and Patricia Poitras Professor of Neuroscience at MIT, Howard Hughes Medical Institute Investigator, Professor, Brain and Cognitive Sciences and Biological Engineering at MIT Core Member, Broad…
KEYNOTE SPEAKER 2: March 25, 2021, 12:10–1:05 pm More information on the Symposium Blog by MiSciWriters “Structure-based discovery of new functions in large RNAs” Kevin Weeks, Ph.D. Kenan Distinguished Professor of Chemistry Chemistry, University of North Carolina The Kevin Weeks Lab TALK ABSTRACT The functions of many RNA molecules – including mRNAs, long non-coding RNAs,…
Photo: Jalihal describing his research based on live cell single particle tracking. Growing up in Chennai, in South India, Ameya Jalihal, Ph.D., has always loved going on nature walks, watching birds, and collecting insects and seashells. While observing nature and biodiversity, young Jalihal had many questions that fueled his passion for life sciences. Inspired by…
More information and required registration are available here. Dr. Melissa Moore, chief scientific officer at Moderna Therapeutics, will be hosted for a virtual seminar on February 10, 2021, 4:00– 5:00pm EST by the University of Michigan Center for RNA Biomedicine as part of the worldwide RNA Collaborative Seminar Series. The title of her talk is:…
In our September 2020 issue of RNA Translated, 2020 the year of the RNA virus, we presented how University of Michigan (U-M) Center for RNA Biomedicine’s scientists pivoted their research to address the COVID-19 pandemic. One of them is Dr. Chinnaiyan and his team of prostate cancer researchers who focused on two proteins that are…
The 2020 Nobel Prize of Chemistry recognizes Emmanuelle Charpentier, Max Planck Unit for the Science of Pathogens, Berlin, Germany, and Jennifer Doudna, University of California, Berkeley, USA, “for the development of a method for genome editing.” Every year, the University of Michigan Complex Systems invites U-M faculty to comment about the Nobel Prizes awards. In…
Only a couple of weeks after defending her Ph.D. thesis in November, Sarah Owen, a graduate student in Chemical Engineering in Dr. Sunitha Nagrath’s lab, landed her dream job. “It all went very fast,” she explained, “I had a seven-hour zoom interview on Thursday, and they offered me the job the following Monday!” In January…
Robb Welty Post-doctoral fellow Chemistry Principal Investigator/Faculty: Nils Walter Google scholar What are your research interests? Academically speaking, my scientific interests lie at the intersection of chemistry, physics, and biology. I suppose that I just enjoy figuring out how systems work. It turns out that physics provides an awesome framework for figuring things out,…
The RNA Collaborative Seminar Series is pleased to welcome its 17th and 18th partners, the Cambridge RNA Club (UK) and the Groupe de Recherche RNA (GDR RNA – France). The Cambridge RNA Club is an informal seminar series bringing together the RNA community in Cambridge and surrounding areas. The GDR RNA aims to bring together French…
A Washington Post video (duration 6’16”) – December 8, 2020 How mRNA helped scientists create a COVID-19 vaccine in record time Our RNA scientists, Alice Telesnitsky, Microbiology and Immunology, and Nils G. Walter, Chemistry, Biophysics & Biological Chemistry and co-director of the Center for RNA Biomedicine, explain how RNA research allows to save millions of…
“Over the years, studies have found that more than 80% of the genome may be involved in transcription, or producing noncoding RNA,” said Andrzej Wierzbicki, a professor in the University of Michigan Department of Molecular, Cellular and Developmental Biology. “So the dilemma was: Is all this noncoding RNA functional? Is it important for something? Or…
The observation of single biomolecules in real-time is crucial for our understanding of the cellular biology that is assembled from these molecules, be they DNA, RNA or protein. The recent development of an array of tools and techniques for single-molecule analysis allows studies at an extremely small scale (nanometers, or 10-9 meters) over short periods…
The Center’s Executive Committee welcomes two new members, Sara Aton, Ph.D., Associate Professor, Molecular, Cellular, and Developmental Biology, College of LSA (left), and Laura Scott, Ph.D., Research Professor, Biostatistics, School of Public Health (right). Read Sara Aton “Featured scientist” profile. We thank again our Executive Committee former members for their important contributions to the Center’s…
Our 5th Annual Symposium will take place Thursday and Friday, March 25th and 26th, 2021, 11:00–2:30 EST. VIRTUAL and NOT RECORDED, free and open to all – registration required. RNA research shapes revolutionary scientific paths, from fundamental science discoveries in the labs to powerful biomedical applications for patients. The rapid rise of RNA-guided genome…
Welcome to our 2019–2020 new members, Dr. Analisa DiFeo, Ph.D., and Dr. Joshi Alumkal, M.D.! In this video (5′ 28″), they present their main research topic, respectively on ovarian cancer and prostate cancer, as well as their motivation and interests in RNA research.
An interview with Peter Todd, M.D, Ph.D., Neurology, Medical School, University of Michigan (U-M), and member of the Executive Committee of the U-M Center for RNA Biomedicine Dr. Todd will serve as co-director of a Fragile X Center without walls with investigators at U-M, Baylor College of Medicine, and Emory University. This Fragile X Center…
Once again, the Nobel Prize recognizes the most revolutionary and innovative scientific discoveries that have the highest potential to transform humankind. Drs. Jennifer Doudna and Emmanuelle Charpentier, both biochemists, were awarded the Nobel Prize in Chemistry 2020 “for the development of a method for genome editing,” known as CRISPR. This RNA-guided tool allows to change…
RNA Translated’s main focus is on “2020, the year of the RNA viruses,” with representative contributions from 10 RNA faculty members. We also feature our two Research Cores and broadly report on the Center’s activity with a few highlights. With this publication, we aim to showcase the outstanding achievements and deep impact of the scientific collaborations…
