“Dr. Cheung goes to Washington!”

“Dr. Cheung goes to Washington!”

Michigan Medicine’s Vivian Cheung and fellow RNA heavy hitters from science and medicine lay out the Human RNome Project roadmap at landmark Congressional Briefing BY PAUL AVEDISIAN   On May 8, 2024, Vivian Cheung, M.D., Professor of Pediatrics, University of Michigan, delivered the welcoming remarks at a Congressional Briefing, “The Urgent Need to Advance RNA Science,”…

U-M Researchers Collaborate on $3 Million Grant to Treat Rare Forms of Cystic Fibrosis

U-M Researchers Collaborate on $3 Million Grant to Treat Rare Forms of Cystic Fibrosis

Center RNA Therapeutics Director Michelle Hastings, and faculty members Rachel Niederer and Alexandra Piotrowski-Daspit address the need for new treatment strategies, and the subsequent barriers that must be overcome for success, by working together as an interdisciplinary team with unique expertise in CFTR physiology, designing RNA therapeutics, identifying targetable regulatory sequences, and developing engineered delivery…

Center co-director, Dr. Mats Lungman’s KLIPP system for CRISPR-Cas 9 featured in informative SciTube video

Center co-director, Dr. Mats Lungman’s KLIPP system for CRISPR-Cas 9 featured in informative SciTube video

Enjoy this video which details KLIPP, a “split enzyme” system pioneered by Center for RNA Biomedicine co-director, Mats Ljungman, Ph.D. During the KLIPP process, two non-functional Cas9 enzymes fused to Fok1 enzymes are brought together by a pair of guide RNAs. These guide RNAs specifically target sequences near structural variant junctions unique to cancer cells….

Pfizer’s Greg DiGennaro gives virtual presentation to Center for RNA Biomedicine on Chemicals Manufacturing and Controls and Good Manufacturing Practices in biomedical R&D.

Pfizer’s Greg DiGennaro gives virtual presentation to Center for RNA Biomedicine on Chemicals Manufacturing and Controls and Good Manufacturing Practices in biomedical R&D.

The Center for RNA Biomedicine hosted Pfizer’s Greg DiGennaro this week, an expert in Chemical Manufacturing and Controls (CMC) and international pharmaceutical regulations, for an informative webinar. Greg discussed navigating regulatory hurdles and Good Manufacturing Practices (GMP) in biomedical research and development. Below, you can find a YouTube video of his presentation, as well as…

Yan Zhang wins prestigious National Science Foundation CAREER award to develop non-Cas9 CRISPR-Cas tools for human genome engineering

Yan Zhang wins prestigious National Science Foundation CAREER award to develop non-Cas9 CRISPR-Cas tools for human genome engineering

ANN ARBOR, Mich., Apr 23, 2024 – We are thrilled to announce that Yan Zhang, Ph.D., Assistant Professor of Biological Chemistry at the University of Michigan, has won a distinguished CAREER Award from the U.S. National Science Foundation (NSF). The U.S. National Science Foundation (NSF) Faculty Early Career Development (CAREER) Program offers awards in support of…

Mats Ljungman, Ph.D., presents talk on breakthrough KLIPP precision cancer-targeting technique at AACR annual meeting

Mats Ljungman, Ph.D., presents talk on breakthrough KLIPP precision cancer-targeting technique at AACR annual meeting

University of Michigan Center for RNA Biomedicine Co-Director Dr. Mats Ljungman presented research on his KLIPP technique at the American Association for Cancer Research (AACR) Annual Meeting at the San Diego Convention Center in California. Dr. Ljungman’s talk, “KLIPP: Precision targeting of cancer with CRISPR,” was given on Tuesday, April 9, as part of the…

An international audience of over 500 attend the 8th Annual RNA Symposium

An international audience of over 500 attend the 8th Annual RNA Symposium

What a thrill it was to welcome our keynote speakers, including the 2023 Nobel Prize laureate for Physiology and Medicine Dr. Drew Weissman, and registrants to the U-M Ann Arbor campus on Friday, March 8, as well as those who joined us LIVE via Zoom. University of Michigan President Santa J. Ono, Ph.D., welcomed speakers and…

Mats Ljungman, Ph.D., awarded watershed $3.7 million grant from NIH for KLIPP cancer therapy study

Mats Ljungman, Ph.D., awarded watershed $3.7 million grant from NIH for KLIPP cancer therapy study

We are thrilled to announce that Mats Ljungman, Ph.D., Co-Director of the Center for RNA Biomedicine at the University of Michigan, has just been awarded a $3.7 million grant from the National Institutes of Health (NIH) for the purpose of continuing his groundbreaking work with precision-targeting KLIPP cancer therapy – the project’s highest funding by…

Nils Walter and Adrien Chauvier publish new review article – and it’s about time… literally!

Nils Walter and Adrien Chauvier publish new review article – and it’s about time… literally!

Center for RNA Biomedicine Co-Director Nils Walter, Ph.D. is excited about sharing some news about yet another fascinating role RNA plays in gene regulation – and it’s about time… literally.  In a new review article, “Regulation of bacterial gene expression by non-coding RNA: It is all about time!” published January 10, 2024 in the journal…

2023-2024 Seminars

Up Next: The 2023-2024 RNA Innovative Seminar Series has concluded. Seminars will resume in September 2024, check back for updates! 2023 Monday, September 11, 4:00 pm, Graham Erwin, Stanford University Monday, September 25, 4:00 pm, Jeffrey Barrick, UT at AustinMonday, October 9, 4:00 pm, Guizhi (Julian) Zhu, University of MichiganMonday, October 23, 4:00 pm, Susan Gottesman,…

Stephen Parker co-lead author of new paper linking gene network and pancreatic beta cell defects to type 2 diabetes

Stephen Parker co-lead author of new paper linking gene network and pancreatic beta cell defects to type 2 diabetes

Center for RNA Biomedicine Faculty and Executive Committee Member Stephen C.J. Parker, Ph.D., Associate Professor, Departments of Computational Medicine & Bioinformatics, Human Genetics, and Biostatistics, just released new findings from a recent study on type 2 diabetes regulatory networks co-led by teams from the University of Michigan and Vanderbilt University. Type 2 diabetes results from a dysfunction of…

Giving Tuesday, November 28

Giving Tuesday, November 28

Every year on Giving Tuesday, millions of people around the world join together to support causes and organizations that are making a difference. At the University of Michigan, impactful projects across all three campuses and Michigan Medicine are funded each year thanks to the generosity of the U-M community on the Tuesday after Thanksgiving.  With a…

Huda Akil, Ph.D., wins National Medal of Science Award

Huda Akil, Ph.D., wins National Medal of Science Award

October 24, 2023, The White House: In a formal ceremony presided over by President Biden, Huda Akil, Ph.D., was honored with the National Medal of Science Award, the nation’s highest scientific honor. A Center for RNA Biomedicine Faculty Member, Dr. Akil’s research focuses on understanding the neurobiology of emotions, including pain, anxiety, depression and substance…

For the Walter Lab, the proof is in the fluorescent pudding
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For the Walter Lab, the proof is in the fluorescent pudding

How do you prove, in a laboratory setting studying objects in size just one-thousandth of the diameter of a hair, that something is doing what it is designed to do? The Walter Lab at the University of Michigan is doing just that, through single-molecule fluorescence imaging and tracking, and recently for a tiny nano engine…

Michigan Medicine Health Lab features CRB faculty work with biomarkers

Michigan Medicine Health Lab features CRB faculty work with biomarkers

Research Update: Sunitha Nagrath and Muneesh Tewari. CRB Faculty Members Sunitha Nagrath, Ph.D., and Muneesh Tewari, Ph.D., M.D., are learning the potential that liquid biopsies hold as a potential non-invasive, diagnostic tool. Their research is cited in a new article recently published in Health Lab. Dr. Nagrath reveals that circulating biomarkers found in bodily fluids…

John Prensner charts a new path toward global standardization for ribosome profiling (Ribo-Seq)
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John Prensner charts a new path toward global standardization for ribosome profiling (Ribo-Seq)

Rooted firmly in his lab suite tucked deep within the core of the Pentagon-esque Medical Sciences Research Building (MSRB) complex on the University of Michigan campus, John Prensner, M.D., Ph.D., is focused on bringing to light an area of genomic investigation involving a hive of “worker bees” called noncanonical ORFs (open reading frames), that play…

Nobel Prize Awarded to 2024 RNA Symposium Speaker Drew Weissman

Nobel Prize Awarded to 2024 RNA Symposium Speaker Drew Weissman

The Nobel Assembly at the Karolinska Institutet has today decided to award the 2023 Nobel Prize in Physiology or Medicine jointly to Katalin KarikĂł and Drew Weissman. 1  Read the full press release. Drew Weissman, M.D., Ph.D., will be featured as a keynote speaker at the Center for RNA Biomedicine’s 8th annual RNA Symposium in March, 2024 at the University of…

LSA researcher Monica Dus named White House Fellow

LSA researcher Monica Dus named White House Fellow

A University of Michigan researcher has been appointed a 2023-24 White House Fellow. Monica Dus, associate professor of molecular, cellular and developmental biology in LSA, was chosen through a highly competitive selection process for her efforts in communicating science to the public. Dus was placed with the Department of the Navy. “I am so honored…