Michelle Paulsen Research Laboratory Specialist Intermediate Bru-Seq Lab – Mats Ljungman Lab (Center for RNA Biomedicine core facility) Radiation Oncology, Medical School Website What is the role of RNA in your research? In the Ljungman Lab, RNA features predominantly as we developed the Bru-seq suite of techniques almost 20 years ago. Bru-seq is a next…
Arushi Varshney, Ph.D. Computational Medicine and Bioinformatics Medical School Faculty-Mentor: Stephen C. J. Parker Google scholar LinkedIn Twitter Through my research, I aim to better understand how predisposition to complex metabolic diseases such as type 2 diabetes (T2D) is encoded in our DNA. I employ computational and statistical approaches to analyze large high-throughput data sets…
Becky Glineburg, Ph.D. Postdoctorate Neurology, Medical School Faculty-Mentor: Peter Todd, M.D., Ph.D. Google Scholar I’m fascinated with how nucleic acid structure dictates various molecular pathways and mechanisms. Currently I’m investigating how GC-rich RNA repeat expansions promote an aberrant form of translation (RAN translation) and how this process contributes to neurodegenerative disease. I am…
Over 1,450 people attended our webinar with Melissa Moore, Chief Scientific Officer at Moderna Therapeutics, on March 3rd, 2021. In her presentation, Dr. Moore explained how the mRNA vaccine works, and how it was developed in record time of just 45 days. To put an end to this pandemic, she strongly encouraged the audience to…
Megan Trotter, Ph.D. Candidate Human Genetics,Medical School Faculty-Mentor – Dr. Sundeep Kalantry LinkedIn Kalantry’s Lab What are your research interests? I study epigenetic factors that influence X-chromosome inactivation. X-inactivation takes place in female mammals to equalize X-linked gene expression to that of males. However, even in cells that have undergone X-inactivation, there is still…
Karen Montoya is a fourth year Ph.D. candidate in Nils Walter’s lab (Department of Chemistry, College of LSA) where she is studying state-of-the-art single molecule spectroscopy and imaging. Montoya’s interests in biosciences were sparked in part by “Osmosis Jones,” an animated action comedy about one white blood cell’s race against the biological clock to hunt…
KEYNOTE SPEAKER 5: March 26, 2021, 11:05–12:00 pm More information on the Symposium Blog by MiSciWriters “Distinguishing self and non-self dsRNA in vertebrates and invertebrates” Brenda Bass, Ph.D. Distinguished Professor of Biochemistry University of Utah The Brenda Bass Lab Twitter: @BassLabUtah TALK ABSTRACT When a virus infects an animal cell, including a human cell,…
KEYNOTE SPEAKER 1: March 25, 2021, 11:05–12:00 pm More information on the Symposium Blog by MiSciWriters “RNA Splicing, Chromatin Modification, and the Coordinated Control of Gene expression” Tracy Johnson, Ph.D., University of California – Los Angeles Keith and Cecilia Terasaki Endowed Chair in the Life Sciences Professor of Molecular, Cell and Developmental Biology Howard Hughes…
By Elisabeth Paymal Altogether, over 6,800 rare diseases affect an estimated 25 million to 30 million Americans. These patients who suffer from genetic mutations that often occur within the same family, are still nowadays left with few, if any, therapeutic options. However, RNA on-going discoveries and the development of new technology and tools such as…
Karen Montoya, Ph.D. Candidate Chemistry, College of LSA Faculty: Nils G. Walter LinkedIn: linkedin.com/in/karen-montoyaa I am interested in chemistry at the interface with biology and medicine. I have always had an interest in understanding the pathology of a disease. Through my research, I am working on a diagnostic tool that detects microRNA (miRNAs) molecular…
KEYNOTE SPEAKER 5: March 26, 2021, 12:10–1:05 pm More information on the Symposium Blog by MiSciWriters “Mechanisms that target RNA for destruction” Christopher D. Lima, Ph.D. Alfred P. Sloan Chair; Chair and Member and Professor, Structural Biology Program, Sloan Kettering Institute; Investigator, Howard Hughes Medical Institute The Christopher Lima Lab TALK ABSTRACT Decay and…
KEYNOTE SPEAKER 3: March 25, 2021, 1:35–2:30 pm More information on the Symposium Blog by MiSciWriters “Exploration of Biological Diversity to Discover Novel Molecular Technologies” Feng Zhang, Ph.D. James and Patricia Poitras Professor of Neuroscience at MIT, Howard Hughes Medical Institute Investigator, Professor, Brain and Cognitive Sciences and Biological Engineering at MIT Core Member, Broad…
KEYNOTE SPEAKER 2: March 25, 2021, 12:10–1:05 pm More information on the Symposium Blog by MiSciWriters “Structure-based discovery of new functions in large RNAs” Kevin Weeks, Ph.D. Kenan Distinguished Professor of Chemistry Chemistry, University of North Carolina The Kevin Weeks Lab TALK ABSTRACT The functions of many RNA molecules – including mRNAs, long non-coding RNAs,…
Ameya Jalihal, Ph.D. (alumnus, graduated in December 2020) Chemistry, College of LSA Faculty: Nils G. Walter Dissertation Defense, Thursday, December 10, 2020 “To find and to form: Strategies for intracellular molecular target search and higher-order assembly” Ameya Jalihal, advisor: Nils G. Walter Google Scholar LinkedIn What are your research interests? I’m interested in how…
Photo: Jalihal describing his research based on live cell single particle tracking. Growing up in Chennai, in South India, Ameya Jalihal, Ph.D., has always loved going on nature walks, watching birds, and collecting insects and seashells. While observing nature and biodiversity, young Jalihal had many questions that fueled his passion for life sciences. Inspired by…
Meredith Purchal Ph.D. Candidate Program in Chemical Biology, College of LSA Faculty: Kristin Koutmou and Markos Koutmos Koutmos lab Koutmou lab Linkedin What are your research interests? I am primarily interested structurally characterizing the interactions between RNA and RNA modifying enzymes using x-ray crystallography. Post transcriptional modification of RNA is widespread and ubiquitous, adding a…
More information and required registration are available here. Dr. Melissa Moore, chief scientific officer at Moderna Therapeutics, will be hosted for a virtual seminar on February 10, 2021, 4:00– 5:00pm EST by the University of Michigan Center for RNA Biomedicine as part of the worldwide RNA Collaborative Seminar Series. The title of her talk is:…
In our September 2020 issue of RNA Translated, 2020 the year of the RNA virus, we presented how University of Michigan (U-M) Center for RNA Biomedicine’s scientists pivoted their research to address the COVID-19 pandemic. One of them is Dr. Chinnaiyan and his team of prostate cancer researchers who focused on two proteins that are…
Jiaqiang Zhu, Ph.D. Candidate Biostatistics, School of Public Health Principal Investigator/Faculty: Xiang Zhou Group (http://xzlab.org ) What are your research interests? My research interests involve the development of efficient statistical methods and computational tools for large-scale genomic studies, including bulk and single cell RNA sequencing, bisulfite sequencing, and spatially resolved transcriptomics. How does RNA relate…
Tasha Thong Graduate Student Environmental Health Sciences, School of Public Health Faculty: Justin Colacino Twitter: @tashathong Instagram: tashathong Google Scholar: Tasha Thong What are your research interests? My research is focused on uncovering the biological basis for racial disparities in breast cancer by exploring the relationship between normal mammary stem cells, genetics, and…
