Rare disease collaboration receives NIH funding for a new Center for Fragile X disease

An interview with Peter Todd, M.D, Ph.D., Neurology, Medical School, University of Michigan (U-M), and member of the Executive Committee of the U-M Center for RNA Biomedicine Dr. Todd will serve as co-director of a Fragile X Center without walls with investigators at U-M, Baylor College of Medicine, and Emory University. This Fragile X Center…

CRISPR in the Nobel spotlight – UM researchers aim to improve CRISPR and use it to target cancer

Once again, the Nobel Prize recognizes the most revolutionary and innovative scientific discoveries that have the highest potential to transform humankind. Drs. Jennifer Doudna and Emmanuelle Charpentier, both biochemists, were awarded the Nobel Prize in Chemistry 2020 “for the development of a method for genome editing,” known as CRISPR. This RNA-guided tool allows to change…

RNA Translated, our magazine and brief report, is out!

RNA Translated’s main focus is on “2020, the year of the RNA viruses,” with representative contributions from 10 RNA faculty members. We also feature our two Research Cores and broadly report on the Center’s activity with a few highlights. With this publication, we aim to showcase the outstanding achievements and deep impact of the scientific collaborations…

Thank you to our postdocs!

On the occasion of the National Postdoc Appreciation Week, September 21st–25th, the University of Michigan (U-M) Center for RNA Biomedicine’s community warmly thanks UM’s postdocs for their tremendous contributions to the field of RNA research and to the life of our scientific community. According to the U-M Postdoctoral Association (UMPDA), an estimated 1,400 to 1,600…

From the Center’s co-directors, Fall 2020

Dear Colleagues, While the COVID-19 pandemic has been causing major disruptions as well as many inconveniences, it also offers some new opportunities; perhaps now is the most opportune time to make new interpersonal connections, start new scientific collaborations, and broaden one’s horizons by learning from others. Through our activities below, we aim to support the…

Our members’ promotions:

Four Associate Professors and one Professor! The Board of Regents of May 21st, 2020, approved recommendations for new appointments and promotions for regular associate and full professor ranks of the University of Michigan. The following Center for RNA Biomedicine’s members were further appointed:   Sami J. Barmada, associate professor of neurology, with tenure, Medical School…

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“Kinetic fingerprinting” of single protein molecules to find the biomarker needle in the haystack

  A cross-disciplinary team of scientists from the University of Michigan (U-M) has developed a biochemical technique that successfully measures the number of individual protein molecules present in blood at low concentrations. These findings are published in the Proceedings of the National Academy of Sciences (PNAS), September 2020. The scientists developed special antibody probes that…

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Stressed cellular proteins break social distancing rules

By Elisabeth Paymal A team of scientists associated with the University of Michigan Center for RNA Biomedicine discovered unexpected cellular adaptation mechanisms in response to dehydration. The observed protein reaction has never been reported before. The research began while observing processing bodies (P-Bodies), which are membrane-less organelles (MLO) involved in RNA degradation in human cells….

S. Moon and N. Walter receive the CZI Collaborative Pairs Pilot Project Award

ANN ARBOR, MI, AUGUST 19, 2020—”A pair” of scientists from the University of Michigan (U-M) Center for RNA Biomedicine receives the Chan Zuckerberg Initiative (CZI) Collaborative Pairs Pilot Project Awards. The U-M Center for RNA Biomedicine brought together two scientists for this highly competitive grant: principal investigator Stephanie Moon, Ph.D., Assistant Professor in Human Genetics,…

Run into Grant Sprints!

The Center for RNA Biomedicine is offering Grant Sprints. For more information, please contact Maria Stieve. Photo: Grant Sprint at the U-M Center for RNA Biomedicine, October 2019, clockwise from left to right, Elizabeth Tidwell, Markos Koutmos, Aaron Frank, Brandon Ruotolo, Varun Gadkari. Curiosity and passion lead scientists to their field of research, but a…

Scientists Come Together to Discuss RNA Science: The RNA Collaborative Seminar Series

RNA is a leading-edge field of biomedical research that is quickly expanding at many public research and academic institutions in the US and Canada. The complexity of this research requires collaborations between scientists across disciplines and specialties, establishing communities of RNA scientists within each of these institutions. When the COVID pandemic required to postpone all…

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miR-181a, a microRNA that regulates ovarian cancer cells

by Elisabeth Paymal One of the hallmarks of ovarian cancer is genomic instability resulting in gain and loss of DNA throughout the entire genome, including many microRNAs (miRNA). Dr. DiFeo, Ph.D., Associate Professor of Pathology and of Obstetrics and Gynecology at Michigan Medicine, and her team, research which miRNAs are involved in the early stages…

Sarah Keane is a 2020 PEW Scholar

Keane is U-M’s 15th scientist to receive this very prestigious award since its inauguration in 1985, and the first one since 2013. “For my lab what this award means is that we can take real chances and pursue these challenging projects that are really difficult in terms of methodology development and other technical challenges that…

Our Members at The RNA Society 25th Annual Meeting

May 27 2:00–4:00 pm, Concurrent Session 2, RNA Structure and Regulation Adrien Chauvier, Pujan Ajmera, Nils Walter, Competition between ligand binding and transcription factor NusA modulates riboswitch-mediated regulation of transcription   8:00–9:00 pm, Poster Session 2, Interconnected Processes Catherine Scull, The N-terminal region of the A12.2 subunit stimulates RNA polymerase I transcription elongation   9:00–10:00 pm, Poster Session 5, RNA…

RNA Collaborative Seminar Series

The RNA Collaborative seminar series goal is to cross promote RNA research and strengthen and connect the RNA scientific community.  More information is available on the RNA Collaborative Seminar Series webpage, supported by The RNA Society. We encourage RNA Centers across the world to join us. If your RNA Center is interested in joining this…

U-M Center for RNA Biomedicine hosts the RNA Collaborative Seminar Series, May 6, 2020

Launched in April 2020, the goal of the RNA Collaborative seminar series is to cross-promote RNA research to strengthen and connect the RNA scientific community. Proposed by the University of Michigan (U-M) Center for RNA Biomedicine, this initiative received great enthusiasm from seven RNA research centers. The group was quickly joined by two more centers…

Two RNA Biomedicine experts are elected to the National Academy of Sciences

The election of professors Janet L. Smith and Arul Chinnaiyan, both members of the Center for RNA Biomedicine Strategic Advisory Board, to the National Academy of Sciences is an outstanding validation of the excellence of the RNA research at the University of Michigan. Members are elected to the National Academy of Sciences in recognition of…