Vivian G. Cheung, M.D. Frederick G.L. Huetwell Professor of Pediatric Research Research Professor, U-M Life Sciences Institute Professor of Pediatrics, U-M Medical School Professor of Human Genetics, U-M Medical School Investigator, Howard Hughes Medical Institute We study regulation of transcription; in particular, RNA-DNA sequence differences, RNA polymerase pausing and R-loop. We are interested in the…
Monica Dus, Ph.D. Assistant Professor Department of Department of Molecular, Cellular, and Developmental Biology The Dus lab is interested in understanding how the environment reshapes brain and behavior. To this end we are studying how diet changes the physiology of the brain by altering metabolic-epigenetic pathways at both the transcriptional and post-transcriptional levels, and how this,…
Jayakrishnan Nandakumar, Ph.D. Associate Professor Departments of Molecular, Cellular and Developmental Biology We are interested in the biogenesis, trafficking, recruitment to telomeres, and catalytic mechanism of the RNP enzyme telomerase. We are also investigating other noncoding RNAs that are involved in gene regulation. Visit Lab Website Follow on Twitter: @LabNandakumar What are your research…
Carlos Andres Aguilar, PhD Assistant Professor Biomedical Engineering College of Engineering The long-term goal of the NOBEL (nano-omic-bio-engineering-laboratory) is to make breakthroughs in medicine and biology that instill hope and inspire others. To accomplish this feat, we develop, optimize and apply innovative technologies such as integrative genomic assays and high-throughput sequencing, micro/nanofabricated devices, genome…
Kaushik Ragunathan Assistant Professor Department of Biological Chemistry My lab is interested in the molecular mechanisms that define how the combinatorial logic of histone modifications and its dynamic interactions with histone binding proteins encodes stable and heritable patterns of gene expression. We take a multidisciplinary perspective that synthesizes genetics, biochemistry and biophysical approaches to capture…
Charles L. Brooks III Cyrus Levinthal Distinguished University Professor of Chemistry and Biophysics Warner-Lambert/Park-Davis Professor of Chemistry Professor of Biophysics, Director of Biophysics Our group studies RNA structure, dynamics and folding using both all atom and coarse grained models. Current interests involve the assembly of the ribosome and it’s functional dynamics, the folding of complex…
We explore single cell transcriptomes through single cell RNASeq. Primarily focused on cancer. Visit Website What are your research interests? I am interested in the interaction between the cancer and the microenvironment. This includes exploring how both macromolecules and physical forces modulate cancer growth. In addition, our lab focuses on single cell analysis technologies…
Xiang Zhou, Ph.D. Associate Professor Departments of Biostatistics We develop statistical methods and computational tools for analyzing array based or sequencing based RNA studies. Example application areas include differential expression analysis, removing batch effects, controlling for individual relatedness or population stratification, single cell RNA sequencing studies. Visit Lab Website Follow on Twitter: @xzlab_org What…
Andrew Ludlow, Ph.D. Assistant Professor, Movement Science Director, Integrative Molecular Genetics Laboratory School of Kinesiology Broadly, my laboratory studies telomere and telomerase biology. We are interested in the gene expression regulation of telomere maintaining genes, such as telomerase component hTERT. We focus on the gene expression regulation by alternative RNA splicing by studying…
POSTPONED UNTIL FURTHER NOTICE: Telomerase Holoenzyme Assembly, Structure, and Action at Telomeres Kathleen Collins (UC Berkeley) Hosted by: Department of Chemistry POSTPONED UNTIL FURTHER NOTICE: NCI RNA Imaging and Intracellular Dynamics Workshop (flyer) Porter Neuroscience Center, Building 35, Rooms 610/620/630 Website: https://ncifrederick.cancer.gov/events/conferences/NCIRNAWorkshop VIRTUAL: RNA Center Journal Club April 2, 4pm, BlueJeans link: https://bluejeans.com/2968484075/…
Aaron Frank, Ph.D. Assistant Professor Departments of Biophysics and Chemistry In order to understand the relationship between molecular structure and dynamics and biological function, the Frank research group seeks to develop and deploy integrative modeling tools to elucidate the structure and dynamics of biologically relevant molecules. We are primarily interested in using our methods to…
Eva L. Feldman, M.D., Ph.D., F.A.A.N. Russell N. DeJong Professor of Neurology Director, Program for Neurology Research & Discovery Director, ALS Center of Excellence Amyotrophic lateral sclerosis (ALS) is a progressive degeneration of motor neurons that develops from a complex interaction of genetic, epigenetic, and environmental factors. We are investigating the role of altered…
Aaron L. Slusher, PhD – Pubmed Research Postdoctoral Research Fellow Ludlow Integrative Molecular Genetics Laboratory School of Kinesiology Who/what brought you to science? Science has always challenged me in the most meaningful way, and I have been fortunate to be associated with great mentors and colleagues to share the excitement for discovery. This has only…
John Moldovan, Ph.D. Postdoctoral Research Fellow Moran Research Group Department of Human Genetics Who/what brought you to science? I have always wanted to know how and why things work. I became seriously interested in science as a career after taking cell biology in college. What are your research interests? I study human LINE-1…
Mengyi Sun Graduate Student Research Assistant Graduate Student Instructor Zhang Lab Department of Ecology & Evolutionary Biology Who/what brought you to science? I was attracted to scientific research after reading (with fun & effort) the ‘Feynman’s lectures on physics’. What are your research interests? My research focuses on the field of evolutionary systems biology….
Petra Vande Zande PhD Candidate Wittkopp Lab Department of Molecular, Cellular, & Developmental Biology Who/what brought you to science? From an early age I have been fascinated with the beauty of the natural world and filled with curiosity about how it works, from ecosystems down to the molecular level. As a high school…
Ryan Mills, Ph.D. Associate Professor of Computational Medicine and Bioinformatics Associate Professor of Human Genetics Our laboratory develops methods for analyzing RNA sequence data, with a focus on quantifying and assessing rates of translation using ribosome footprinting techniques. We are also actively studying novel mechanisms of translational regulation at the transcriptional level. Visit Lab Website…
Jiaqi Shi, M.D., Ph.D. Assistant Professor, Gastrointestinal and Hepatobiliary Pathology, Surgical Pathology Department of Pathology Our lab is interested in studying how epigenetic alterations in pancreatic cancer affect transcription and how this effect contributes to pancreatic cancer development. Visit Website View Michigan Research Experts Profile Follow on Twitter: @jiaqishi What are your research interests?…
Marissa Cloutier Ph.D. Candidate Kalantry Lab Department of Human Genetics Who/what brought you to science? I got hooked on science while taking a developmental biology course at Albion College. The following semester I began doing research with the professor who taught the course and I have been involved in science ever since! What…
Sundeep Kalantry, Ph.D Associate Professor Associate Chair for Research Department of Human Genetics Our research aims to define how epigenetic regulation occurs in mammals. We use X-chromosome inactivation, which results in transcriptional silencing of most genes along one of the two X-chromosomes in female mammals, to gain insights into epigenetic processes, including through chromatin modifications…
