“Not all proteins are born alike: Evolution solutions in translational control” flyer (6/6/19)
Dr. Michal Linial (The Hebrew University of Jerusalem)
Hosted by: DCMB Seminar series
June 3rd RNA Innovation Seminar
Foster & Dandpat
RNA Innovation Seminar || Theme: Biochemistry (flyer) (6/3/19)
1.) “Investigating the Coactivator Med25 – Activator Recognition Features”
Nick Foster, Ph.D. candidate, from the Anna Mapp lab
2.) “Local-to-global signal transduction at the core of the Mn2+ sensing
riboswitch”
Shiba Dandpat, Ph.D. candidate from the Nils Walter lab
RNA & Human Genetics Faculty Candidate Seminar (5/30/19)
“Spatiotemporal regulation of mRNA function in health and neurological disease” (abstract)
Stephanie Moon, PhD, Howard Hughes Medical Institute Post-doctoral Fellow
University of Colorado, Boulder
RNA Innovation Seminar || Theme: Genetics
1.) “Meta-prediction of gene expression levels from genotypes across multiple tissues and datasets”
Andrew Liu, Ph.D. candidate in Biostatistics from the Hyun Kang lab
2.) “Maternal Control of Paternal X-inactivation”
Marissa Cloutier, Ph.D., from the Sundeep Kalantry Lab
Symposium: Reinventing Drug Discovery through Chemical Biology (5/16/19)
11:30 am Amanda Garner, PhD “Identification of Kinase-Targeted Drug Combinations using Chemoproteomics”
Sponsor: Cayman Chemical
“Epigenomics” (5/16/19)
Stephen C.J. Parker, PhD, Assistant Professor, Department of Computational Medicine & Bioinformatics, and Department of Human Genetics.
Hosted by: Taubman Tech Talks
“A novel CRISPR/Cas9 approach for targeting cancer” (5/13/19)
Mats Ljungman, Ph.D.
Hosted by:RCC Grand Rounds at NCRC
Video-rate AFM Workshop for Dynamic Imaging (5/7/19)
Sponsored by the Single Molecule Analysis in Real-Time (SMART) Center, a University of Michigan Biosciences Initiative Research Core and Oxford Instruments.
Elucidating RNA structure and the molecular recognition properties of multi-domain enzymes: nucleic acid binding interactions at the chromatin interface (flyer) (5/7/19)
Nick Reiter (Marquette University)
Hosted by: Chemistry seminar series
MCDB Connell Symposium (5/6/19)
“The two faces of Xist RNA”
Jeannie Lee, M.D., Ph.D. (Harvard)
Novel Insights into Regulatory RNAs Using Novel high-throughput tools in vivo flyer (4/30/19)
Lydia Contreras (University of Texas)
Hosted by: Biological Chemistry seminar series
Chemical Approaches to Interrogating the Transcriptome flyer (4/30/19)
Robert Spitale (University of California Irvine)
Hosted by: Chemistry seminar series
RNA Innovation Seminar || Theme: Cell Biology flyer (4/29/19)
1.) “A NOVA1-PTBP1-PTBP2 Axis in Telomerase Alternative Splicing”
Mohammed E. Sayed, Ph.D., from the Andrew Ludlow Integrative Molecular Genetics Laboratory
2.) “Epigenetic hijacking of developmental HOX programs promotes Ewing sarcoma tumorigenesis”
April Apfelbaum, Graduate Student–Cancer Biology Program from the Beth Lawlor lab
Chemical Regulation of Functional RNAs flyer (4/23/19)
Yunsun Nam (UT Southwestern)
Hosted by: Chemistry seminar series
RNA Innovation Seminar flyer (4/22/19)
1.) “The Mechanism of RAN Translation at Repeat Expansion Mutations”
Katelyn Green, Ph.D. candidate from the Peter Todd Lab Keywords: Translation initiation, neurodegeneration, repeat RNAs
2.) “Isolation of exosomes from blood by integrating acoustics and microfluidics” abstract
Mengxi Wu, Ph.D., Postdoctoral Fellow, Kurabayashi Lab, and previously Duke University Acoustofluidics Lab
Super-Resolution Microscopy Made Simple (4/18/19)
Josh Vaughan (University of Washington)
Hosted by: Chemistry seminar series Faculty Host: Julie Biteen
RNA Innovation Seminar || Co-sponsored with the Department of Cellular and Developmental Biology (4/8/2019)
“Are Stress Granules up to PAR?” abstract
Anthony Leung, PhD, Associate Professor, Johns Hopkins
Viral Subversion of Nuclear Pathways: Opportunities for Therapy (4/4/2019)
Beatriz M.A. Fontoura, Ph.D. (University of Texas-Southwestern
Hosted by: Department of Microbiology and Immunology
The Origin Recognition Complex: Where It All Begins (4/2/19)
Leemor Joshu-Tor, Cold Spring Harbor Laboratory
Hosted by: Biological Chemistry Ludwig Lectureship seminar series
4th Annual RNA Symposium – Foundational RNA Biosciences: From Discovery to Function (3/29/19)
Featuring Keynote speakers:
1.) Rachel Green, PhD, Johns Hopkins University
2.) David Bartel, PhD, Massachusetts Institute of Technology
3.) Howard Chang, PhD, Stanford University
4.) Kristen Lynch, PhD, University of Pennsylvania
5.) Alice Telesnitsky, PhD, University of Michigan
3/25/19 RNA Guest speaker
Ron Breaker
RNA Innovation Seminar || External Speaker (3/25/19)
“Comprehensive Discovery of Bacterial Ribozymes and Riboswitches“ (abstract)
Ronald Breaker, PhD, Yale University
The Short and the Long of Telomeres: Structures, Mechanisms, and Disease Implication (flyer) (3/22/19)
Feng Qiao (UC, Irvine)
Hosted by: MCDB seminar series
Dynamics of rRNA-protein interactions during transcription (3/22/19)
Sarah Woodson (Johns Hopkins University)
Hosted by: Biophysics seminar series
“A Transcript for All Reasons: RNA Biomedicine” flyer (3/21/19)
Nils Walter & Mats Ljungman, co-directors of the U-M RNA Center for Biomedicine.
Hosted by: Taubman Tech Talks
RNA Faculty Candidate Seminar (3/20/19)
“Spatiotemporal regulation of mRNA function in health and neurological disease” (abstract) Stephanie Moon, PhD , Howard Hughes Medical Institute Post-doctoral Fellow
University of Colorado, Boulder
Studies of RNA methylation and chromatin architecture (3/18/19)
Chuan He (University of Chicago)
Hosted by: Chemistry seminar series
RNA Faculty Candidate Seminar (03/13/19)
“Uncovering post-transcriptional regulatory mechanisms underling human diseases Through CRISPR-based screening strategies” (abstract)
Thomas Gonatopoulos-Pournatzis, PhD , Postdoctoral Fellow, Blencowe Laboratory
Donnelly Centre, University of Toronto
March 11th Guest speaker
Jeffrey, Kieft (Colorado)
RNA Innovation Seminar || External Speaker (3/11/19)
“A novel mode of RNA maturation in viruses…and beyond?” flyer
Jeffrey Kieft, PhD, University of Colorado
Deciphering patterns in selective small molecule:RNA interactions (flyer) (03/03/19)
Amanda Hargrove (Duke University)
Hosted by: Chemistry seminar series
Mar 4th RNA Innovation Seminar
Nagrath & Cani
RNA Innovation Seminar || Theme: Transcriptome analysis (flyer) (3/4/19)
1.) “RAS-AGO2 interaction-What’s the RISC?” Sunita Shankar, Ph.D. Research Investigator from Arul Chinnaiyan lab
2.) “Development of a Whole-Urine, RNA-based Next Generation Sequencing Assay for Early Detection of Aggressive Prostate Cancer” Andi Cani, Ph.D. candidate from Scott Tomlins lab
Feb 27, 2019 Guest speaker, Samie Jaffrey, MD, PhD, (Cornell)
“The dynamic epitranscriptome: Control of gene expression through regulated and reversible mRNA modifications” abstract (2/27/219)
Samie Jaffrey, MD, PhD, Greenberg-Starr Professor, Pharmacology, Weill Cornell Medicine
Co-hosted by Center for RNA Biomedicine & UM Chromatin Club
“Elucidating the Interplay Between RNA Structure and Gene Expression During Vertebrate Embryogenesis” (2/26/19)
Jean Denis Beaudoin, PhD (Giraldez Lab, Yale University)
Hosted by: BiolChem Faculty Candidate Seminar
“Anatomy of the long noncoding RNA” (flyer) (2/19/19)
Mauro Calabrese, Ph.D. (University of North Carolina, School of Medicine, Chapel Hill)
Hosted by: Department of Human Genetics Seminar Series
Faculty Host: Sundeep Kalantry
“Rhythmic Transcriptomes: Circadian or Sleep-Wake Driven?” (2/8/19)
Paul Franken (Universite de Lausanne, Switzerland)
Hosted by: MCDB Seminar Series
Feb 4th RNA Seminar
Morgan & Robertson
RNA Innovation Seminar || Theme: Medicinal Chemistry (flyer) (2/4/19)
1.) “Rational Approaches to Design and Synthesize RNA-Biased Small Molecule Libraries” abstract
Brittany Morgan, Ph.D. from the Anna Mapp lab
2.) “Towards the Treatment of HIV: Isolation and Structural Characterization of Natural Product Nef Inhibitors” abstract
Andrew Robertson, Ph.D. Postdoctoral Fellow from the David Sherman lab
MCDB Faculty Candidate Seminar (1/24/19)
“Organizational Principles of 3D Genome Architecture”
Jordan Rowley, PhD (Corces Lab, Emory)
MCDB Faculty Candidate Seminar (1/22/19)
“Structural Insights into the 7SK Core RNP, a Major Regulator of Eukaryotic Transcription”
Catherine Eichorn, PhD (Feigon Lab, UCLA)
BiolChem Faculty Candidate Seminar (1/22/19)
“Structure-Based Discovery of RNA Regulatory Mechanisms.”
Anthony Mustoe, PhD (Weeks Lab, UNC)
RNA Innovation Seminar || Theme: Microbiology (flyer) 1/21/19
1.) “RNA virus mutation rates, new approaches to some old problems”
Adam Lauring, M.D., Ph.D., Associate Professor
Departments of Internal Medicine and Microbiology and Immunology
2.) “Seq-ing to Find Population Development During Biofilm Formation”
Janet Price, Ph.D. candidate, from Matthew Chapman lab
Pathology Research Seminar (1/17/19)
“The ribosome makes and the ribosome breaks”
Zissimos Mourelatos (University of Pennsylvannia)
Chromatin Biology symposium (1/14/19)
Invited Speakers: Stavros Lomvardas (UCSF), Alexander Ruthenburg (UChicago), Bassem Al-Sady (UCSF), Xiaobing Shi (Van Andel), Albert Basson (Kings College), Berenice Benayoun (USC), Charles Gersbach (Duke), Natalia Ivanova (Yale), Kelvin Kwan (Rutgers), Jessica Tyler (Cornell)
Predicting RNA Structure with Physics and Sequence Comparison (1/11/19)
David Mathews (University of Rochester Med School)
Dec 17th RNA Seminar
RNA Innovation Seminars || Theme: Biochemistry (flyer) (12/17/19)
1.) Monika Franco, PhD candidate from the Kristin Koutmou Lab
“Modification of mRNA can alter translation elongation, fidelity, and termination” (abstract)
2.) Gulzhan Raiymbek, PhD, from the Ragunathan Lab
“A non-enzymatic function associated with a putative histone demethylase regulates heterochromatin spreading and inheritance” (abstract)
MCDB Faculty Candidate Seminar (12/11/18)
“Single-cell decomposition of vertebrate cell fate hierarchies and control logic”
David Wagner, PhD (Klein Lab, Harvard University)
Biological Chemistry Seminar series (12/11/18)
Mechanisms of Branch Site Selection by the Spliceosome
Aaron Hoskins (University of Wisconsin-Madison)
Chemistry seminar series (12/10/18)
Bringing Biochemistry into the Genomic Era
Dan Herschlag (Stanford University)
Microbiology & Immunology Seminar (12/6/18)
Visualizing the Assembly of Influenza Viral RNA (flyer)
Seema Lakdawala (University of Pittsburgh)
Faculty Host: Adam Lauring, M.D., Ph.D
Biological Chemistry seminar series (12/4/18)
Single-cell heterogeneity in proliferation-quiescence decisions
Sabrina Spencer (University of Colorado, Boulder)
Faculty Host: Peter Freddolino
RNA Innovation Seminars || Theme: Structural Biology (12/3/18)
Dec 3rd RNA Seminar
Zhang & Purchal
1.) Huaqun Zhang, PhD postdoc from the Keane Lab
“Biophysical study of the RNA thermosensor prfA-UTR”
2.) Meredith Purchal, PhD candidate co-mentored by Markos Koutmos and Kristin Koutmou
“Deciphering the Structure and Function of mRNA-Modifying Pseudouridine Synthases” (Abstract)
Department of Chemistry Seminar (12/3/18)
Dynamics of 3D genome organization at single-molecule resolution in living cells (abstract)
Anders Hansen (UC Berkley)
Biological Chemistry seminar series (11/27/18)
Shaping the Genome Through DNA Repair
Sylvie Doublie (University of Vermont)
Nov 26th RNA Innovation Seminar
Kuo & Lamb
RNA Innovation Seminars || Theme: Genetics (11/26/18)
1.) Molly Kuo, MD/PhD candidate from the Antonellis Lab, Human Genetics
“Determining the role of cysteinyl-tRNA synthetase (CARS) variants in human disease” (Abstract)
2.) Abby Lamb, PhD candidate from the Wittkopp Lab, Ecology & Evolutionary Biology “Coordinate regulation of genes controlling Drosophila pigmentation development by microRNAs” (Abstract)
Department of Chemistry Seminar (11/20/18)
Roles of elusive translational GTPases (LepA and BipA) come to light (flyer)
Kurt Fredrick (The Ohio State University)
Nov 19th RNA Seminar
Painter & Kalinksi
RNA Innovation Seminars || Theme: Cell Biology (11/19/18)
1.) Mark Painter, PhD candidate from the Kathleen Collins research group Title of talk: “Contributions of the hematopoietic stem and progenitor cell HIV reservoir to persistent viremia in treated HIV patients” Keywords: RNA virus, HIV, Latency, Viremia, Reverse transcription, RNA secondary structure, tRNA priming (abstract)
2.) Ashley Kalinski, Ph.D. Postdoctoral Research Fellow, from the Giger Lab Title of talk: “Dual Leucine Zipper Kinase: Elucidating the local role of a major player of axon regeneration” (abstract)
Nov 13th “Beer & Science” event
Special event || “Beer & Science”
hosted by Qiagen (11/13/18)
Conor O’Neill’s
Department of Chemistry Seminar (11/12/18)
RNA tertiary structure and its role in molecular recognition: lessons from self-splicing group II introns and lncRNA molecules
Anna Marie Pyle (Yale University)
Hosted by: Dept of Chemistry Moses Gomberg Lecture Series
Biological Chemistry Seminar (11/6/18)
Defective RNA Binding of ALS FUS Mutant Induces Aberrant Phase Separation
Sua Myong (Johns Hopkins University)
Faculty Host: Kaushik Ragunathan
Biological Chemistry Seminar (10/30/18)
Building Polycomb Repressed Chromatin
Nicole Frances (McGill)
Faculty Host: Kaushik Ragunathan
Department of Chemistry Seminar (10/16/18)
Understanding spliceosome mechanism with small molecule inhibitors
Melissa Jurica (UC Santa Cruz) || Faculty host: Nils Walter
Oct 15th RNA Innovation Seminar
Zhao & Maldovan
RNA Innovation Seminar || Theme: Molecular Biology (10/15/18)
1.) “Myc plays an important role in myocyte reprogramming and extraocular muscle regeneration” (abstract)
Yi Zhao, PhD (Kahana Lab)
2.) “RNA ligation precedes U6 snRNA/LINE-1 retrotransposition” (abstract)
John Moldovan, PhD (Moran Lab)
Symposium: Thurs, Oct 11th 9:00 AM – 4:30 PM, BRSB “Protein Folding Diseases Initiative Symposium”
RNA Innovation Seminars || Theme: Computational Analysis (10/1/18)
1.) “Human skeletal muscle eQTL meta-analysis reveals long-range genetic regulations”)
Li Guan, PhD candidate from the Laura Scott research group) (abstract)
2.) “Heritability estimation and differential analysis of count data with generalized linear mixed models in genomic sequencing studies” (abstract)
Shiquan Sun, Ph.D., Postdoctoral fellow from the Zhou Lab
Biophysics seminar (9/28/18)
“Folded Viral RNAs that Sense the Host Cell Machinery: Windows into RNA Structure-Based Regulation”
Jeffrey Kieft (University of Colorado) || Faculty host: Nils Walter
Chemistry seminar (9/24/18)
“RNA as a Drug Target and Material for Nanotechnology”
Thomas Hermann (UC San Diego)
Faculty Host: Aaron Frank (flyer)
MCDB seminar (9/21/18)
“Exploring and Exploiting the Pentatricopeptide Repeat Proteins: Programmable RNA-Binding Proteins that Emerged Through Nuclear-Organellar Coevolution”
Alice Barkan (University of Oregon)
Faculty Host: Andrzej Wierzbicki
MedChem Seminar (9/20/18)
“Chemical Probing of Translational Control and microRNA Biology”
Amanda L. Garner, PhD; Assistant Professor, Department of Medicinal Chemistry, College of Pharmacy
RNA Innovation Seminars || Theme: Transcriptome Analysis (9/10/18)
1.) “Epigenetic Reprogramming in Mutant IDH1 Glioma Enhances DNA-Damage Response”
Felipe J Núñez, Ph.D.(Postdoctoral fellow from the Castro/Lowenstein lab)
Keywords: Glioma, mutant IDH1, histone methylation, epigenetic reprogramming, DNA-damage, genomic stability, radio-resistance
2.) “Not just reads: associate single-cell RNA-seq data with cell images using Fluidigm C1″
Hongjiu Zhang, Ph.D. candidate (PhD student from the Guan Lab)
Keywords: Fluidigm C1, imaging, cell size, quantification
2017-2018 RNA Innovation Seminar Series
June 18th RNA Seminar
Ohi & Kitzman
RNA Innovation Seminars (6/18/18)
Melani Ohi, Ph.D., Associate Professor of Cell and Developmental Biology, Research Associate Professor, Life Sciences Institute Using Cryo-EM to study RNA based molecular machines
Jacob Kitzman, Ph.D., Assistant Professor of Human Genetics, Assistant Professor of Computational Medicine and Bioinformatics Massively parallel measurement of mutations’ functional effects
June 4th RNA Seminar
Tai & Collins
RNA Innovation Seminars|| Theme: RNA viruses/retroviruses (6/4/18)
Andrew Tai, M.D., Ph.D., Assistant Professor, Department of Internal Medicine, Division of Gastroenterology, Department of Microbiology and Immunology, Program in Cellular and Molecular Biology, University of Michigan Medical School “How positive-strand RNA viruses hijack the host cell to build viral replication sites”
Kathleen Collins, M.D., Ph.D., Associate Director, Cellular and Molecular Biology Program, Professor of Internal Medicine and Professor of Microbiology and Immunology, Medical School “Peripheral Blood and Bone Marrow Reservoirs of HIV”
May 21st RNA Seminar
Guest Lecturer Arno Greenleaf, Duke University
RNA Innovation Seminars|| Guest Lecturer (5/21/18) Arno Greenleaf, Ph.D. Professor of Biochemistry, Department of Biochemistry, Duke University Medical Center “CDK12 and the machines of transcription, splicing and mRNA nuclear export” hosted by: Mats Ljungman Seminar Flyer
May 14th RNA Seminar
Collins & Mills
RNA Innovation Seminars|| Theme: RNA in neuroscience (5/14/18)
Catherine Collins, Ph.D., Associate Professor of Molecular, Cellular and Developmental Biology “Mechanisms of axonal stress signaling”
Ryan Mills, Ph.D., Assistant Professor of Computational Medicine and Bioinformatics, Assistant Professor of Human Genetics “Exploring the dynamics of protein translation in a model of neuronal differentiation”
Apr 30th RNA Seminar
Tewari & Spengler
RNA Innovation Seminars|| Theme: Extracellular RNA (4/30/18)
Muneesh Tewari, M.D., Ph.D., Ray and Ruth Anderson-Laurence Sprague Memorial Research Professor, Professor of Internal Medicine “Extracellular RNAs as biomarkers and the road to clinical application”
Ryan Spengler, Ph.D., Research Fellow, Internal Medicine, Medical School “exRNA-seq Analysis in Human Biofluids”
RNA Innovation Seminars (4/16/18)
Indika Rajapakse, Ph.D. Assistant Professor of Computational Medicine & Bioinformatics, Assistant Professor of Mathematics Dynamics and reprogramming of the human genome
Sathiya Pandi Narayanan, Ph.D., Research Fellow, Michigan Center for Translational Pathology “LADDER, a lung cancer prognostic LncRNA regulates DNA damage response”
Apr 2nd RNA Seminar
Colacino & Buttitta
RNA Innovation Seminars|| Theme: Epigenetics (4/2/18)
Justin Colacino, Ph.D., Assistant Professor, Environmental Health Sciences, Assistant Professor, Nutritional Sciences, Using single cell transcriptomics to understand environmental effects on the stem cell epigenome
Laura Buttitta, Ph.D., Assistant Professor of Molecular, Cellular and Developmental Biology, “Unveiling metamorphosis: Examining chromatin and gene expression dynamics and their coordination with the cell cycle in the developing Drosophila wing” (abstract)
RNA Innovation Seminars|| Theme: Computational analysis of RNA (3/19/18)
Mar 19th RNA Seminar Scott & Jiang
Laura Scott, Ph.D., Assistant Professor, Department of Biostatistics, School of Public Health, Genetic regulation of gene expression and methylation in skeletal muscle
Hui Jiang, Ph.D., Assistant Professor, Department of Biostatistics, School of Public Health, Robust identification of biomarkers using RNA-Seq data
Mar 5th RNA Seminar
Hero & Cai
RNA Innovation Seminars (3/5/18)
Dawen Cai, Ph.D., Assistant Professor, Cell & Developmental Biology, “A Single Cell Perspective of Neuronal Connections and Subtypes in the Drosophila Brain”
Al Hero, Ph.D., John H. Holland Distinguished University Professor R. Jamison and Betty Williams Professor of Engineering, “Node centrality analysis for biological networks”
Feb 19th RNA Seminar
Beer & Tomlins
RNA Innovation Seminars|| Theme: RNA in cancer (2/19/18)
David Beer, Ph.D., Professor of Surgery, Section of Thoracic Surgery, Professor of Radiation Oncology, “Insights into Racial Differences in Esophageal Adenocarcinoma”
Scott Tomlins, M.D., Assistant Professor, Genitourinary Pathology, MCTP Clinical Laboratory – Oncomine Cancer Panel Test, Anatomic Pathology, “RNA: The forgotten molecule of precision oncology”
Dept of Chemistry Moses Gomberg Lecture Series: Thurs, Feb 15th 4PM, Chemistry 1640 Phil Belivacqua, Ph.D, Penn State University “Elucidation of catalytic strategies of small nucleolytic ribozymes from combined experimental and theoretical approaches”
RNA center promoted seminar: BioChem speaker Wendy Gilbert from Yale gives beautiful talk on her serendipitous discovery of abundant pseudo-U modifications of mRNAs.
Biological Chemistry Seminar: Tues, Feb 6th 12PM, North Lecture Hall, MS II Wendy Gilbert, Ph.D, Yale University “Regulated mRNA Modifications: New Functions for Ancient RNA Modifying Enzymes”
Feb 5th RNA Seminar
Menon & Trievel
RNA Innovation Seminars|| Theme: RNA in gene regulation (2/5/18)
Rajasree Menon, Ph.D., Assistant Research Scientist of Computational Medicine & Bioinformatics, “Seq-ing the human kidney single cells”
Raymond Trievel, Ph.D., Associate Professor, Biological Chemistry, “Structural and Functional Studies of Nocturnin, a Ribonuclease Implicated in Obesity”
Human Genetics Seminar: Monday, February 5th 4PM, South Lecture Hall (3699 MS II) Mike McCarthy, MD, Robert Turner Professor of Diabetic Medicine, University of Oxford, UK “Diamonds in the dirt: from genetics and genomics to biology and translation in type 2 diabetes”
MCDB Seminar: Friday, February 2nd 12:15PM, 1640 Chem Christine Queitsch, PhD, Associate Professor, Department of Genome Sciences, University of Washington “Contrasting Regulatory DNA Variation and Flexible Transcription Factor Function”
Jan 22nd RNA Seminar
Telesnitsky & Ono
RNA Innovation Seminars|| Theme: RNA viruses/retroviruses (1/22/18)
Alice Telesnitsky, Ph.D., Professor of Microbiology and Immunology, Medical School “HIV-1 RNA fates and folds”
Akira Ono, Ph.D., Associate Professor of Microbiology and Immunology, Medical School “Driving HIV-1 Gag to the plasma membrane: lipids and RNA are in charge” Keywords: tRNA, basic patch, virus assembly, and acidic phospholipids.
Jan 8th RNA Seminar
Xiang Zhou
RNA Innovation Seminars|| Theme: Computational analysis of RNA (1/8/18)
Xiang Zhou, Ph.D., Assistant Professor of Biostatistics “MACAU: Differential Expression Analysis and Expression Heritability Estimation for RNAseq Studies” (abstract)
Dec 18th RNA Seminar
Smith and Keane
RNA Innovation Seminars|| Theme: RNA structural biology and mechanism (12/18/17)
Janet Smith, Ph.D., Margaret J Hunter Collegiate Professor in the Life Sciences, Professor of Biological Chemistry, Medical School, Research Professor, Life Sciences Institute and Professor of Biophysics A Novel Mode of RNA Binding Assists APOBEC3H in the Molecular Arms Race Against HIV
Sarah Keane, Ph.D., Assistant Professor of Biophysics and Assistant Professor of Chemistry Hybrid Tools Promoted Biological Chemistry Seminar: Tues, Dec 12th 12PM, North Lecture Hall, MS II Ailong Ke, Ph.D., Cornell “Structure and Mechanism of RNA-Based Adaptive Immunity, the CRISPR-Cas System”
RNA Innovation Seminars|| Theme: RNA in neuroscience (12/4/17)
presented by:
David Turner, Ph.D., Research Associate Professor, Molecular and Behavioral Neuroscience Institute Associate Professor, Biological Chemistry “microRNAs, microRNA targets, and neuron formation during mammalian retinal development”
Robert Thompson, Ph.D., Research Associate Professor, Psychiatry and Research Associate Professor, Molecular and Behavioral Neuroscience Institute “Regulation of the astrocyte transcriptome”
Nov 20th RNA Seminar
Wierzbicki & Veatch
RNA Innovation Seminars|| Theme: RNA in gene regulation (11/20/17)
Andrzej Wierzbicki, Ph.D., Associate Professor Molecular, Cellular, and Developmental Biology “The role of non-coding RNA in transcriptional gene silencing”
Sarah Veatch, Ph.D., Associate Professor of Biophysics and Physics “Super-resolution fluorescent localization imaging: The basics, some headaches, a few tricks, and plans for the future”
Mini-Course Seminar: Tues, Nov 14th 12:00 PM – 1:00 PM, North Lecture Hall, Med Sci II Burckhard Seelig, Ph.D., The BioTechnology Institute; Univ of Minnesota Primordial enzymes made in a test tube from random libraries of RNA and protein (Seminar Flyer)
Nov 13th RNA Seminar
Kumar & Lowenstein
RNA Innovation Seminars|| Theme: RNA in cancer (11/13/17)
Chandan Kumar, Ph.D., Assistant Professor, Cancer Biology, MI-ONCOSEQ Clinical Sequencing Core Director, Experimental Pathology Clinical Sequencing for Precision Oncology: Growing footprint of RNA-seq” (Abstract)
Pedro Lowenstein, M.D., Ph.D., Richard C. Schneider Collegiate Professor of Neurosurgery, Professor, Cell and Developmental Biology “Small is Beautiful: The Power of Being Less than 200 Nucleotides Long” Keywords: RNA, Cancer, lnc-RNA, cRNA, Brain, 42 (Abstract)
Quatitative Biology Seminar: Mon, Nov 13th, 12 PM, 335 West Hall Tim Stasevich, Ph.D., Colorado State “Real-time imaging of single mRNA translation dynamics in living cells”
Biological Chemistry Seminar: Tues, Nov 7th 12PM, North Lecture Hall, MS II Alan Zahler, Ph.D., University of California, Santa Cruz “Genetic and Molecular Approaches to Understanding Splice Site Choice”
Chemistry Seminar: Wed, Nov 1st 4 PM, 1640 Chemistry Sylvia Rouskin, Ph.D., MIT Whitehead Institute “RNA structure heterogeneity”
Oct 30 RNA in Epigenetics
Dou & Iwase
RNA Innovation Seminars|| Theme: Epigenetics (10/30/17)
Yali Dou, Ph.D., Professor, Pathology, Professor, Biological Chemistry, “Epigenetic deregulation in AML”
Shigeki Iwase, Ph.D., Assistant Professor of Human Genetics, “Michigan-made nascent RNA sequencing revealed neuronal activity-dependent transcription start sites”
Chembio Seminar: Wed, Oct 25th 4 PM, 1640 Chemistry Ming Hammond, Ph.D., University of California, Berkeley “Illuminating the Single-Cell Biology of Chemical Signals in Bacterial and Immune Cells” (Seminar Flyer & Abstract)
Mini-Course Seminar: Tues, Oct 24th 12:00 PM – 1:00 PM, North Lecture Hall, Med Sci II Charles Carter, Ph.D., Biochemistry and Biophysics; UNC “Interdependence, Reflexivity, Fidelity, Impedance Matching, and the Evolution of Genetic Coding” (Course Flyer)
Symposium: Fri, Oct 20th 9:00 AM – 12:00 PM, BRSB “A. Alfred Taubman Medical Research Institute’s Annual Symposium & 10th Anniversary Celebration Featuring the awarding of the $100,000 Taubman Prize” (event details)
Dr Mark Schlissel & RNA Center co-director Nils Walter at the 10th Anniversary Taubman Institute Symposium celebrating the success of the Center for RNA Biomedicine. Who could forget President’s Schlissel’s Welcome Address at our Inaugural Symposium?
10/20/17 Tenth anniversary symposium and 2017 Taubman Prize ceremony for the A. Alfred Taubman Medical Research Institute at the A. Alfred Taubman Biomedical Science Research Building in Ann Arbor, MI.
Mini-Course Seminar: Tues, Oct 17th 12:00 PM – 1:00 PM, North Lecture Hall, Med Sci II Loren Williams, Ph.D., Chemistry and Biochemistry; Georgia Tech (Course Flyer)
RNA Innovation Seminars|| Theme: RNA for Beginners , Vol 2 (10/16/17)
RNA for Beginners, Vol 2
Ljungman & Li
Oct 16, 2017
Mats Ljungman, Ph.D., Founding Co-Director of the Center for RNA Biomedicine, Professor, Departments of Radiation Oncology and Environmental Health Sciences, Translational Oncology Program “From Cradle to Grave”
Jun Li, Ph.D., Professor of Human Genetics, Associate Professor & Associate Chair for Research of Computational Medicine and Bioinformatics, Faculty, Center for Statistical Genetics; Comprehensive Cancer Center, Member, Depression Center; Michigan Diabetes Research Center; Michigan Metabolomics & Obesity Center “Single-cell genomic data analysis: theory, algorithm and application”
Symposium: Thurs, Oct 12th 9:00 AM – 4:30 PM, BRSB “Protein Folding Diseases Initiative Symposium” Register here by Oct 2nd
Mini-Course Seminar: Tues, Oct 10th 12:00 PM – 1:00 PM, North Lecture Hall, Med Sci II David Deamer, Ph.D., Physical and Biological Sciences; UC, Santa Cruz “Hydrothermal fields, not vents: A terrestrial origin of life” (Course Flyer)
RNA Innovation Seminars|| Theme: Applications of RNA-Seq (10/2/17)
Maureen Sartor, Ph.D., Associate Professor of Computational Medicine and Bioinformatics, Medical School Associate Professor of Biostatistics, School of Public Health, Assistant Director for Graduate Education, Computational Medicine and Bioinformatics “Using RNA-seq to study HPV-positive tumor subtypes and HPV integration in head and neck cancer” Abstract
Katsuo Kurabayashi, Ph.D., Professor, Mechanical Engineering, Associate Chair for Graduate Education, Mechanical Engineering, Professor, Electrical Engineering and Computer Science
“A versatile toolbox for droplet-based single-cell mRNA sequencing” Abstract
Course Sponsored by the Cellular & Molecular Biology and Genetics Training Programs: Tue, Sept 26th 3:00 PM – 4:00 PM, Room M3330 Medical Science I, Long Cai, Ph.D., Caltech “Spatial Genomics: single cell in situ transcription profiling and lineage analysis”
RNA Innovation Seminars|| Theme: RNA in gene regulation (9/18/17)
9/18/17 RNA Innovation Seminar
Sally Camper, PhD
Margery Shaw Distinguished University Professor of Human Genetics
Sally Camper, Ph.D., Margery Shaw Distinguished University Professor of Human Genetics, Professor of Internal Medicine “Role of RNA splicing in Pituitary Insufficiency and Growth Disorders”
Seminar: Thurs, Sept 14th 12:00 PM – 1:00 PM, 5330 Med. Sci. I Britt Glaunsinger, Ph.D., UC Berkeley “Controlling the message: viral manipulation of host gene expression during infection”
Mini-Course Seminar: Tues, Sept 12th 12:00 PM – 1:00 PM, North Lecture Hall, Med Sci II Ramanarayanan Krishnamurthy, Ph.D., Chemistry; Scripps Research Inst. “Origins of Life – Giving Rise to Biological Chemistry from Pre-Biological Chemistry” (Course Flyer)
RNA for Beginners, Vol 1
Nils Walter, Ph.D.
RNA Innovation Seminars|| Theme: RNA for Beginners , Volume 1 (9/11/17)
presented by Founding Co-Director of the Center for RNA Biomedicine:
Nils Walter, Ph.D., Professor of Chemistry, Biophysics, and Biological Chemistry; Founding Director, Single Molecule Analysis in Real-Time (SMART) Center “RNA for Beginners, Volume 1″ (Seminar Flyer)
DCMB Seminar: 3:30-4:30pm Wed, Sep 6th, Forum Hall, Palmer Commons. Hyun Min Kang, Ph.D., Associate Professor of Biostatistics “Robust and powerful single cell RNA-seq studies by leveraging natural genetic variation” (Kang Flyer/abstract)
RNA Innovation Seminars (6/8/17): Palmer Commons, Fourth Floor Forum Hall –Max Wicha, MD “Regulation of breast cancer stem cells by non-coding RNA’s” (Abstract, Flyer)
5/18/17 RNA Seminar Grill and Dahl
Thurs, May 18, 2017: Michigan League – Michigan Room (2nd Floor) –Sheri A. Grill “The long and short of human TPP1” and Jan Dahl “The anti-inflammatory drug mesalamine targets bacteria polyphosphate accumulation” (Grill Abstract, Dahl Abstract, Seminar Flyer)
Thurs, May 4, 2017: Palmer Commons, Fourth Floor Forum Hall –Trisha
Wittkopp “Effects of new mutations on gene expression” and Jianzhi (George) Zhang “Human coding RNA editing is generally nonadaptive”(Wittkopp Abstract, Zhang Abstract, Seminar Flyer)
—> Promoted Seminar : Thursday, May 4th 4-5pm, Chemistry Seminar, 1640 Chemistry, Onn Brandman, PhD, Assistant Professor of Biochemistry, Stanford University “Ribosome-Associated Protein Quality Control” (Seminar Flyer)
Visiting Professor Peter Cook, PhD
April 20, 2017
Apr 20, 2017: Palmer Commons, Fourth Floor Forum Hall – Visiting Professor, Peter Cook, Ph.D., Distinguished Professor of Cell Biology The Sir William Dunn School of Pathology, University of Oxford “Transcription factories: genome organization and gene regulation”(Seminar Flyer, Peter Cook VIEW TALK HERE)
—> Promoted Seminar : Monday, Apr 17th 4-5m, Human Genetics Seminar, 5915 Buhl Classroom,Michael Nachman, Ph.D., UC Berkeley “Gene regulation and the genetic basis of speciation and adaptation in house mice, Mus musculus” (Seminar Flyer, M. Nachman)
—> Promoted Seminar : Wednesday, Apr 12th 10:30am-11:30am, Neurology Seminar, Danto Auditorium in the Cardiovascular Center, J. Paul Taylor, M.D. Ph.D. Investigator, Howard Hughes Medical Institute Chair, Department of Cell and Molecular Biology, Edward F. Barry Chair of Cell and Molecular Biology, St. Jude Children’s Research Hospital “Altered RNA granule dynamics underlie the most common forms of ALS and FTD” (Seminar Flyer, J. Paul Taylor)
—> Promoted Seminar : Thursday, Apr 6th 2pm-3pm, LSI Seminar, Palmer Commons, Fourth Floor Forum Hall, David M. Shechner, Ph.D., Broad Institute and Department of Stem Cell and Regenerative Biology, Harvard University : “New Methods for Probing and Harnessing Noncoding RNA Function” (Seminar flyer, Shechner)
Apr 6th RNA Seminar
Figueroa-Romero and Turner
Apr 6, 2017: Palmer Commons, Fourth Floor Forum Hall – Claudia Figueroa-Romero “RNA regulation and miRNA transport in ALS” and David Turner “MicroRNAs in the developing mammalian retina” (Seminar Flyer)
—> Distinguished University
March 28th Gil Omenn
Distinguished U Lecture
Professorship Lecture: Tuesday, Mar 28th 4pm-5pm: Rackham Building, Amphitheatre, Gilbert Omenn MD PhD: “Proteins, Policy, and Paths Less Travel’d: My Career as a Physician Scientist” (Omenn Flyer)
—> Promoted Seminar : Friday, Mar 17th 4pm-5pm: LSA Biophysics Seminar, Chemistry Building Room 1300, Dr. Rhiju Das, Associate Professor, Stanford University : “Towards RNA Structure/Function from Scratch” (Seminar flyer, Das)
—> Promoted Symposium :Friday, Mar 17 8am – 12pm BSRB : Forbes-Taubman Symposium in Cancer Discovery, co-sponsored by the A. Alfred Taubman Medical Research Institute and the Forbes Institute for Cancer Discovery
Mar 16, 2017: Palmer Commons, Fourth Floor Forum Hall –Yan Zhang “The Biology, Mechanism and Application of the meningococcal CRISPR-Cas9system” and Sarah Keane “NMR studies of regulatory RNAs” (3-16-17-RNA Innovation Seminar Flyer)
—> Promoted Seminar : Tuesday, Mar 14th 12pm-1pm: Department of Biological Chemistry Seminar Series, North Lecture Hall, Lasse Lindahl PhD, Professor, Department of Biological Sciences, University of Maryland Baltimore County : “Ribosomal Stress: Ribosome Formation, Function, and Stability, and their Effects on Cell Cycle Control” (Seminar flyer, Lasse Lindahl)
—> Promoted Seminar : Wednesday, Mar 8th 12 – 1:30pm: BioInterfaces Institute (BI), NCRC B18-122 : Digital/Droplet PCR technology and Applications with the RainDance/BioRad company
March 2nd RNA Seminar
Giraldez and Rangunathan
Mar 2, 2017: Palmer Commons, Fourth Floor Forum Hall – Dr. Maria Giraldez “Challenges and opportunities of exRNA-seq” and Kaushik Ragunathan “Epigenetic inheritance uncoupled from small RNA dependent positive feedback loops” (Seminar Flyer)
—> Promoted Seminar : Feb 23 12pm – 1pm: Department of Biological Chemistry, North Lecture Hall – FACULTY
CANDIDATE : Junjie Guo, Ph.D. Whitehe
ad Institute MIT. “The Folding Landscape of RNA G-Quadruplexes in Cells”
—> Promoted Seminar :Feb 17 4pm – 5pm: Department of Chemistry, 1640 Chemistry –Daniele Fabris, University at Albany, SUNY. “MS-based approaches for the elucidation of nucleic acid higher-order structure and dynamics”
Feb 16: Palmer Commons, Fourth Floor Forum Hall – Daniel Lorenz,
Feb 16th RNA Seminar
Lorenz and Scharf
Graduate Student, Biological Chemistry “Method development for the identification of pre-miRNA binding proteins and small molecule modulators” and Nate Scharf Graduate Student, College of Pharmacy “In vitro detection of bacterial RNA polymerase transcription using an RNA aptamer” (Seminar Flyer)
Feb 2nd RNA Seminar
Dus and Freddolino
Feb 2, 2017: Palmer Commons, Fourth Floor Forum Hall – Monica Dus “Let them eat cake: sugar’s effects on the brain” and Peter Fredolino “The cake is a lie: Bacterial starvation responses mediated by pervasive antisense transcription” (Seminar Flyer)
—> Promoted Seminar : Jan 25th 3:30pm – 4:30pm: Department of Computational Medicine & Bioinformatics, Forum Hall, Palmer Commons Building – Terrence Furey, PhD, University of North Carolina Chapel Hill “Epigenetic and transcriptional reprogramming define molecular subtypes of Crohn’s disease.” (Seminar Flyer, Terrence Furey, PhD)
Jan 19, 2017: Palmer Commons, Fourth Floor Forum Hall –
Jan 19th RNA Seminar
Wagnon and Cieslik
Jacy Wagnon “Brain transcriptomes after seizures”
Marcin Cieslik“Transcriptome sequencing at the juncture of clinical translation”
—> Promoted Seminar : Jan 10th 12pm-1pm: Department of Biological Chemistry, North Lecture Hall – Jens Christopher Schmidt PhD, University of Colorado “Biochemical and Biophysical Mechanisms of Telomerase Recruitment to Telomeres.” (Jens Christopher Schmidt Seminar Flyer)
Dec 15th RNA Seminar
Kretzler and Parker
Dec 15, 2016: Palmer Commons, Fourth Floor Forum Hall –Matthias Kretzler“Integrative network analysis of tissue based mRNA: Identification of disease processes and biomarkers across disciplines and continents”and Steve Parker“Genetic regulatory signatures underlying islet and muscle gene expression and type 2 diabetes” (Seminar Flyer)
Dec 1, 2016: Palmer Commons, Fourth Floor Forum Hall – Alon Kahana
December 1st RNA Seminar
Kahana and Fogarty
“RNA profiling and regulatory networks in a Zebrafish muscle regeneration model”and Liz Fogarty“Defining the molecular mechanisms of promoter usage in Schwann cells”(Seminar Flyer)
—> Promoted Seminar : Nov 30, 2016: Medical School, Cell and Developmental Biology, BSRB Seminar Rooms ABC 12pm-1pm – Eva Nogales, Ph.D.“Molecular visualization of microtubules and transcription complexes using cryo-EM”
—> Promoted Seminar : Nov 29, 2016: Medical School, Biological Chemistry, North Lecture Hall 12pm-1pm – Christine Mayr, M.D., Ph.D.“3’UTR-Mediated Protein-Protein Interactions Regulate Protein Functions.”
Nov 17, 2016: Palmer Commons, Fourth Floor Great Lakes Central – Scott Horowitz“RNAs as chaperones” and Lyle Simmons“Ribonucleotide excision repair in Bacillus subtilis” (Seminar Flyer)
November 3rd RNA Seminar
Kwan and Sutton
Nov 3, 2016: Palmer Commons, Fourth Floor Forum Hall – Ken Kwan“Analysis of local transcriptomes in neuronal dendrites”and Michael Sutton“Tuning neurotransmission through local mRNA translation at synaptic sites” (Seminar Flyer)
Oct 20, 2016: Palmer Commons, Fourth Floor Forum Hall – Kristin Koutmou“Ribosomes pause and slide on lysine-encoding homopolymeric A stretches” and Julia Widom“A Single-Molecule View of Transcription Regulation by the preQ1 Riboswitch” (Seminar Flyer)
Oct 6, 2016: Location ABC in BSRB – Amanda Garner“Progress Toward
October 6th RNA Seminar
Garner and Frank
the Discovery of microRNA-21-Selective Small Molecules”and Aaron Frank“Probing the Structure of Therapeutically Important RNAs Using Integrative Modeling and Simulations.”
Sep 22nd Guest Speaker:
Dr. Arjun Raj : “Single cell analysis of therapy resistance in cancer”
Sep 22, 2016: Palmer Commons, Fourth Floor Forum Hall – Guest Speaker: Dr. Arjun Raj : “Single cell analysis of therapy resistance in cancer”
September 8, 2016: Palmer Commons, Fourth Floor Forum Hall – Mike Wolfe : “A novel approach to the analysis of RNAProtein Interactions,”Jenna Clem : “Metabolic Regulation of Neuronal Activity,” and Elizabeth Abshire : “Structural and Functional Characterization of a Human Exoribonuclease Implicated in Obesity”
August: No seminars
July: No seminars
June 30, 2016: Palmer Commons, Fourth Floor Forum Hall – Edgar Otto : “Microfluidic droplet generation technology (Drop-Seq) enables high-throughput single cell transcriptomics” and Peter Freddolino : “The logic of transcriptional regulation in bacteria: From molecules to cells”
June 23, 2016: Palmer Commons, Fourth Floor Forum Hall – John Moran : “Studies of a Human Retrotransposon” and Eric Fearon : “Working toward improved mouse models of somatic tissue mosaicism and cancer development”
June 16, 2016: Palmer Commons, Fourth Floor Forum Hall – Shigeki Iwase : “Taming enhancers by histone H3K4 methylation reversal”and Tom Wilson : “The influence of RNA transcription on replication timing and genomic instability at very large genes”
June 2, 2016: 1300 Chemistry Building – Guest Speaker Daniel R. Schoenberg Ph. D. : “The CAPtivating impact of cytoplasmic mRNA recapping on the transcriptome and the proteome”
May 26, 2016: Palmer Commons, Fourth Floor Forum Hall – Guest Speaker David Arnosti Ph. D. : “Transcriptional enhancers: new insights from thinking genome-wide and up-close and personal”
May 19, 2016: Palmer Commons, Fourth Floor Forum Hall –Daniel Lorenz : “High-Throughput Platform Assay Technology for microRNA-Targeted Drug Discovery”and Muneesh Tewari : “Extracellular RNA”
May 12, 2016: 1300 Chemistry Building – Bob Lyons : “Opportunities for RNA biology at the U of M Sequencing Core ” and Peter Todd : “How RNA repeats trigger translation and drive neurodegeneration”
May 5, 2016: Palmer Commons, Fourth Floor Forum Hall – Ebrahim Azizi : “Exploring tumor cells Heterogeneity using Single Cell technologies”and Kamlesh Bisht : “sunRNA mediated regulation of human TPP1”
April 28, 2016: Palmer Commons, Fourth Floor Forum Hall – Mats Ljungman Ph.D. : “The nascent RNA Bru-seq technology platform” and Scott Barolo : “Cis-regulatory control of gene transcription: decoding the enhancer”
April 21, 2016: Palmer Commons, Fourth Floor Forum Hall – Nils Walter Ph. D. : “Single Molecule Microscopy Reveals the Mechanisms of Non-Coding RNA Nanomachines” and Sundeep Kalantry Ph. D.“To Xist or not to Xist: an X-chromosome Inactivation Tale”
April 14, 2016: 1300 Chemistry Building –Michael Kearse, Todd lab : “Using CRISPR/Cas9 for visualizing RNA in live cells”and Hilary Archibald, Barmada lab : “Assessing global RNA metabolism in human iPSC models of ALS/FTD using BruChase-seq”