MCubed Block – the foundation that would lead to the Center for RNA Biomedicine

MCubed stimulates innovative research and scholarship by distributing real-time seed funding to multi-unit, faculty-led teams.  Through this revolutionary research funding program, faculty from at least two different campus units can form a collaborative trio, or “cube,” and request either $60K or $15K to advance their idea right away.

The projects below represent RNA-related science developed as a block of MCubed 2.0 under the umbrella of the Center for RNA Biomedicine.

Annotating long non coding RNAs (lncRNA) in zebrafish using an adult muscle regeneration model

Biological relevance of circulating exosomes in the pathology of amyotrophic lateral sclerosis

Control of Cell Cycle and Direct Reprogramming at the Single Cell Level.

Massive human single-cell transcriptome analysis of healthy and diseased kidney tissues applying droplet microfluidic technology (Drop-Seq)

Precise in situ transcriptome mapping by correlated fluorescence imaging
and single cell RNA sequencing

Single-molecule counting of cancer biomarker RNAs in human biofluids

The role of environmental toxins on natural killer cell polarization in ALS

Similar Posts

Amelia and Makenzie Kahn playing outdoors surrounded by trees and nature

U-M researchers develop a personalized RNA therapeutic used to treat twins with an ultra-rare form of Batten disease

September 25, 2024 ANN ARBOR, Mich. — In a remarkable display of bench to bedside science, a therapeutic developed by U-M’s Michelle Hastings, Ph.D., is now being used to treat twin girls with a rare form of juvenile Batten disease. Hastings, who is the Pfizer Upjohn Research Professor of Pharmacology, Director of RNA Therapeutics at…

RNA Featured Researcher – Samantha Grudzien, Neuroscience Graduate Program

Samantha Grudzien Graduate Student Researcher U-M Neuroscience Graduate Program, Peter Todd Lab   Who/what brought you to science? Although not scientists, my mother has been in the medical field for over 30 years and my father has been a computer programmer. From their influence, I had an interest in STEM, and as I continued my…

LSA researcher Monica Dus named White House Fellow

LSA researcher Monica Dus named White House Fellow

A University of Michigan researcher has been appointed a 2023-24 White House Fellow. Monica Dus, associate professor of molecular, cellular and developmental biology in LSA, was chosen through a highly competitive selection process for her efforts in communicating science to the public. Dus was placed with the Department of the Navy. “I am so honored…

John Prensner charts a new path toward global standardization for ribosome profiling (Ribo-Seq)
|

John Prensner charts a new path toward global standardization for ribosome profiling (Ribo-Seq)

Rooted firmly in his lab suite tucked deep within the core of the Pentagon-esque Medical Sciences Research Building (MSRB) complex on the University of Michigan campus, John Prensner, M.D., Ph.D., is focused on bringing to light an area of genomic investigation involving a hive of “worker bees” called noncanonical ORFs (open reading frames), that play…

2016 Inaugural Symposium

Featuring Nobel Laureates Craig Mello and Phillip Sharp “Can RNA Answer It All? From the Origin of Life to a Future of Personalized Medicine” Did you miss the 2016 Inaugural Symposium? Catch the keynote talks here: The Center for RNA Biomedicine Inaugural Symposium brings together national leaders of the scientific, medical and engineering communities working on…

|

How sleep loss sabotages new memory storage in the hippocampus

While some students may think it’s a good idea to pull an all-nighter before an exam, conventional wisdom may be correct: a good night’s sleep may actually be more helpful, according to University of Michigan research. U-M scientists Sara Aton and James Delorme found when mice are sleep deprived, there is an increase in activity…