From the Center’s co-directors, Fall 2020
Dear Colleagues,
Dear Colleagues,
Markos Koutmos, Ph.D. Assistant Professor of Biophysics & Chemistry Markos Koutmos joined the Center’s Executive Committee in 2020. The Koutmos lab is interested in understanding how the 3D structure and dynamics of proteins and RNAs drive their biological function. His lab combines chemistry, biophysics and biology approaches to build a foundation of basic knowledge for…

September 25, 2024 ANN ARBOR, Mich. — In a remarkable display of bench to bedside science, a therapeutic developed by U-M’s Michelle Hastings, Ph.D., is now being used to treat twin girls with a rare form of juvenile Batten disease. Hastings, who is the Pfizer Upjohn Research Professor of Pharmacology, Director of RNA Therapeutics at…
The grassroots Center for RNA Biomedicine at the University of Michigan involves among its opt-in membership RNA scientists from across the Ann Arbor campus, encompassing all seven Schools and Colleges that are engaged in the Biosciences. The Center’s leadership reflects this diversity of viewpoints and serves to facilitate scientific collaboration.

How do you prove, in a laboratory setting studying objects in size just one-thousandth of the diameter of a hair, that something is doing what it is designed to do? The Walter Lab at the University of Michigan is doing just that, through single-molecule fluorescence imaging and tracking, and recently for a tiny nano engine…
“Over the years, studies have found that more than 80% of the genome may be involved in transcription, or producing noncoding RNA,” said Andrzej Wierzbicki, a professor in the University of Michigan Department of Molecular, Cellular and Developmental Biology. “So the dilemma was: Is all this noncoding RNA functional? Is it important for something? Or…

Update 5.8.25 The LUMICKS C-Trap® optical tweezers microscopy instrument is now up and running at the SMART Center Installation of the LUMICKS C-Trap® is now complete at the SMART Center, a CRB core facility. The instrument allows researchers to measure or exert extraordinarily small forces combined with simultaneous multicolor fluorescence imaging. The system boasts up to…