Single Molecule Analysis in Real-Time (SMART) Center
The SMART (Single Molecule Analysis in Real-Time) Center is an NSF-seeded, shared-use facility providing university researchers with single molecule detection and manipulation tools to track and analyze biomolecules with unprecedented detail. The SMART Center provides access to state-of-the-art instrumentation, including single molecule spectroscopy and imaging, laser tweezers, and atomic force microscopy; as well as experienced support in experimental planning and analysis.
We would also be happy to give your group a short demonstration of our capabilities and discuss potential applications.
Services Offered
- Single molecule fluorescent imaging and tracking
- Fluorescence lifetime imaging
- Fluorescence correlation spectroscopy
- Force spectroscopy
- Atomic force microscopy
- Optical tweezers
Assistance with
- Experimental planning
- Data Acquisition
- Data Analysis
Equipment Provided
- TIRF / HILO fluorescence microscope with multicolor EMCCD cameras
- ISS Alba time-resolved confocal microscope
- AFM Workshop TT-AFM atomic force microscope
- MiniTweezers optical tweezers
- Single Particle Nanomanipulator optical tweezers + fluorescence microscope
- Image analysis and particle tracking software
Areas of expertise
- Single molecule techniques
- Fast high-resolution fluorescent imaging
- Single particle fluorescent tracking
- Fluorescence lifetime imaging
- Force spectroscopy
- Experimental planning
- Single molecule data analysis
- Training
Who we serve
University of Michigan and external academic & commercial researchers in all scientific areas, with an added emphasis on RNA Biomedicine.
Contact
Damon Hoff
Phone: (734) 763-5449
Website
SMART Center Brochure
Location
Room 3080 Chemistry
930 N. University Avenue
Ann Arbor, MI 48109
College: LSA, Biophysics
Photo: Dr. Pitchiaya in the SMART lab using lasers