2024-2025 Seminars

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Monday, October 21 | 4 p.m. — Laura Scott, Ph.D. | University of Michigan School of Public Health

Monday, October 21 | 4 p.m.

In-Person: Kahn Auditorium, BSRB
Hybrid: Click here to join via Zoom.

Talk Title: “Regulation of RNA levels in muscle and adipose tissues by sex and genetic variants”

Abstract:
Gene expression is regulated by multiple factors including genetic variation, sex, and cell type. I will describe differences by sex in human skeletal muscle cell type composition, cell type-level gene expression and chromatin accessibility, and bulk miRNA expression in 287 people. I will describe regulation of subcutaneous adipose gene expression by genetic variants in a meta-analysis of >2,200 people. These studies help to better understand transcription and post-transcriptional regulation of gene expression by sex and genetic regulation of gene expression.

About Dr. Scott’s Research:
Dr. Scott uses a combination of bulk and single nucleus omic data – RNA expression, chromatin accessibility, metabolites and DNA methylation – to understand the cellular genetic regulatory landscape and to infer biological connections between genetic variation and disease risk.

2024

Monday, September 23 | 4 p.m. — Gregor Neuert, Ph.D. | Vanderbilt University
Monday, October 7 | 4 p.m. — Joe Yesselman, Ph.D. | University of Nebraska-Lincoln
Monday, October 21 — Laura Scott, Ph.D. | University of Michigan
Monday, November 4 — Nils Walter, Ph.D. | University of Michigan
Monday, November 18 — Jennifer Phillips-Cremins, Ph.D. | University of Pennsylvania
Monday, December 2 | 4 p.m. — Yan Zhang, Ph.D. | University of Michigan

2025

Monday, February 17, 2025 | 4 p.m. — Sundeep Kalantry, Ph.D. | University of Michigan
Monday, April 28, 2025 | 4 p.m. — Connie Wu, Ph.D. | University of Michigan

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