RNA Featured Researcher – Guoming Gao, Biophysics Graduate Program

Guoming Gao
Biophysics Graduate Program, advisor: Nils G. Walter
Google Scholar
LinkedIn
Twitter

Who/what brought you to science? The Encyclopedia of Human Body, my favorite book when I was a kid. It showed me a fascinating world of cell biology where different human cells cooperate to achieve and maintain body functions..

What are your research interests? RNA localization is important for RNA function, and thus it’s critical for cells to orchestra how and when different RNAs get to their destination. Biomolecular condensates in cells can be either RNA ‘roadblocks’ or ‘traps’ that either exclude or retain a specific RNA molecule, both of which extend the time a single RNA molecule needs to reach its destination. I am interested in how biomolecular condensates impact each single RNA’s function by changing their diffusion or transportations, and how we could extract this information by single molecule tracking of RNAs in live cells.

What do you hope is the outcome/impact of your research? Revealing how condensates impact single RNA diffusion paves the way for a completely new angle to understand the biological function of cellular condensates and the mechanism of RNA translocation.

What advice would you give to students who’d like to get more involved in research? Be resilient. Don’t give up the science if that’s really what motivates you and keep you high every day. Life events could emerge and hit you unexpectedly, but what doesn’t kill you makes you stronger.

What profession other than your own would you like to attempt? A broadcaster or podcaster hosting a scientific channel.

What are your longer-term career aspirations? To become a professor or investigator in a research university or institute. I am passionate for contributing to the scientific community either by providing a new angle to a question or by empowering new researchers for the field. I love having a scientific problem in my head that could sometimes keep me awake at night when I get a new idea to solve it.

 

Similar Posts

Scientists Come Together to Discuss RNA Science: The RNA Collaborative Seminar Series

RNA is a leading-edge field of biomedical research that is quickly expanding at many public research and academic institutions in the US and Canada. The complexity of this research requires collaborations between scientists across disciplines and specialties, establishing communities of RNA scientists within each of these institutions. When the COVID pandemic required to postpone all…

Center co-director, Dr. Mats Lungman’s KLIPP system for CRISPR-Cas 9 featured in informative SciTube video

Center co-director, Dr. Mats Lungman’s KLIPP system for CRISPR-Cas 9 featured in informative SciTube video

Enjoy this video which details KLIPP, a “split enzyme” system pioneered by Center for RNA Biomedicine co-director, Mats Ljungman, Ph.D. During the KLIPP process, two non-functional Cas9 enzymes fused to Fok1 enzymes are brought together by a pair of guide RNAs. These guide RNAs specifically target sequences near structural variant junctions unique to cancer cells….

Tracy Johnson, Ph.D. – Keynote speaker, 2021 RNA Symposium

KEYNOTE SPEAKER 1: March 25, 2021, 11:05–12:00 pm More information on the Symposium Blog by MiSciWriters “RNA Splicing, Chromatin Modification, and the Coordinated Control of Gene expression” Tracy Johnson, Ph.D., University of California – Los Angeles Keith and Cecilia Terasaki Endowed Chair in the Life Sciences Professor of Molecular, Cell and Developmental Biology Howard Hughes…

RNA Faculty Spotlight – Chase Weidmann, Biological Chemistry

  Chase Weidmann, Ph.D. Assistant Professor Biological Chemistry, Medical School RNA Faculty Scholar Department Website Google Scholar We are interested in how cellular signals are propagated through interaction networks at the RNA-protein interface, and how these networks malfunction during cancer and disease. In cancer cells, changes in RNA-binding protein stoichiometry and modification status reorganize the…

RNA Innovation Seminar Series

The Center for RNA Biomedicine offers bi-weekly RNA Innovation Seminars that feature visiting professors, U of M faculty, and students. The seminars cover a broad array of topics about RNA research and its application. In addition to learning about the latest research in the field, it is an opportunity to meet colleagues, network, and foster…

Refer your colleagues to join the U-M Center for RNA Biomedicine.

When you join the University of Michigan Center for RNA Biomedicine, you join an RNA research community of over 150 faculty and their labs, across seven Schools and Colleges. This is a great opportunity to network, learn about each other’s expertise and research, and collaborate on innovative grant proposals. Membership in the Center for RNA Biomedicine…