Eva L. Feldman, M.D., Ph.D., F.A.A.N. Russell N. DeJong Professor of Neurology Director, Program for Neurology Research & Discovery Director, ALS Center of Excellence Amyotrophic lateral sclerosis (ALS) is a progressive degeneration of motor neurons that develops from a complex interaction of genetic, epigenetic, and environmental factors. We are investigating the role of altered…
Ryan Mills, Ph.D. Associate Professor of Computational Medicine and Bioinformatics Associate Professor of Human Genetics Our laboratory develops methods for analyzing RNA sequence data, with a focus on quantifying and assessing rates of translation using ribosome footprinting techniques. We are also actively studying novel mechanisms of translational regulation at the transcriptional level. Visit Lab Website…
Jiaqi Shi, M.D., Ph.D. Assistant Professor, Gastrointestinal and Hepatobiliary Pathology, Surgical Pathology Department of Pathology Our lab is interested in studying how epigenetic alterations in pancreatic cancer affect transcription and how this effect contributes to pancreatic cancer development. Visit Website View Michigan Research Experts Profile Follow on Twitter: @jiaqishi What are your research interests?…
Sundeep Kalantry, Ph.D Associate Professor Associate Chair for Research Department of Human Genetics Our research aims to define how epigenetic regulation occurs in mammals. We use X-chromosome inactivation, which results in transcriptional silencing of most genes along one of the two X-chromosomes in female mammals, to gain insights into epigenetic processes, including through chromatin modifications…
Anthony Antonellis, Ph.D James V. Neel Collegiate Professor of Human Genetics Chair, Department of Human Genetics Professor of Neurology, Medical School Our group is broadly interested in how human genetic variation affects gene and genome function. One area of research is grounded in the observation that mutations in aminoacyl-tRNA synthetases cause myriad disease…
Peter Todd, M.D., Ph.D Bucky and Patti Harris Professor of Neurology Our lab studies how nucleotide repeat expansions lead to neurological disease with an aim of developing novel treatments based on mechanistic insights. Specifically, we study how repeats as RNA bind to proteins and prevent them from performing their normal functions. We also study how…
Jianzhi (George) Zhang, Ph.D. Marshall W. Nirenberg Collegiate Professor Professor of Ecology & Evolutionary Biology Our lab is interested in evolution of gene expression and expression noise, RNA modification, and translation regulation. Visit Lab Website What are your research interests? My research area is molecular and genome evolution. I am particularly interested in the…
Sally Camper, Ph.D. Margery W. Shaw Distinguished University Professor Professor of Human Genetics Professor of Internal Medicines Our lab is interested in single cell RNA sequencing for understanding cell differentiation in health and disease. Visit Lab Website View Michigan Research Experts Profile Follow on Twitter: @sallycamper What are your research interests? Regulation of…
Shigeki Iwase, Ph.D., Associate Professor of Human Genetics Our group studies histone methylation-mediated mechanisms underlying mRNA production, i.e. transcription, in the brain. Given that many histone methyl regulators are mutated in cognitive disorders, our research may yield important insights into how histone methylation is involved in normal and pathological brain development and function. Visit…
