John Prensner co-senior author on a major new paper in Nature: Thousands of new proteins revealed in the dark proteome

John Prensner, M.D., Ph.D., is co-senior author of a major paper published in Nature, reporting the discovery of more than 1,700 new proteins in the dark proteome, which could have implications for human diseases, including cancer.

The study is the work of the TransCODE Consortium, an international collaboration of more than 60 researchers at over 30 institutions worldwide, co-led by the Princess Máxima Center for Pediatric Oncology in the Netherlands, the University of Michigan Medical School, the EMBL European Bioinformatics Institute in Hinxton, and the Institute for Systems Biology in Seattle.

“We’re just beginning to see what this ‘dark proteome’ has to offer,” says Prensner. “It’s like the trailer to a movie. We see the outline of a game-changing view of human biology. We’re incredibly excited that the coming years will open new doors to help solve and treat human diseases such as cancer.”

The story has been gaining a lot of attention from the scientific community, with coverage in STATThe EconomistPhys.org and many other news outlets. Read more in the official press release from the Princess Máxima Center for Pediatric Oncology. Congratulations to Dr. Prensner and colleagues!

John Prensner, M.D., Ph.D., Barry J. Glick Early Career Professor of Pediatric Oncology and Assistant Professor of Pediatrics and Biological Chemistry; Center for RNA Biomedicine Executive Committee, University of Michigan

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