The Dihydroorotate Dehydrogenase Inhibitor Brequinar Is Synergistic with ENT1/2 Inhibitors
UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer
Translational control in aging and neurodegeneration
Magnetic resonance imaging of human neural stem cells in rodent and primate brain
The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD
4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes
Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis
Coupling of translation quality control and mRNA targeting to stress granules
Translational Opportunities for Microfluidic Technologies to Enable Precision Epigenomics
Early life metal dysregulation in amyotrophic lateral sclerosis
Wnt Signaling Drives Prostate Cancer Bone Metastatic Tropism and Invasion
Skin wound healing triggers epigenetic modifications of histone H4
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection
A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis
Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases
Mutations predictive of hyperactive Ras signaling correlate with inferior survival across high-risk pediatric acute leukemia
Interaction between Transcription and Translation Machineries on a Nascent RNA with Higher Order Structure
Automated phenotyping and lifespan assessment of a C. elegans model of Parkinson’s disease
Cyclin‐dependent kinase 4 inhibits the translational repressor 4E‐BP1 to promote cap‐dependent translation during mitosis–G1 transition
High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation
Translating Science to Medicine: When Will the Rubber Meet the Road?
Pseudouridinylation of mRNA coding sequences alters translation
Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome
Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data
Validation of a serum 4-microRNA signature for the detection of lung cancer
Ann Arbor, MI
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