RNA Innovation Seminar: Junjie Guo, Yale University School of Medicine

RNA Plasticity in Neuronal Health & Disease Junjie Guo, Ph.D. Assistant Professor Department of Neuroscience Yale University School of Medicine In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Spatial and temporal regulation of gene expression at both transcriptional and post-transcriptional levels underlies the development and functions of the nervous system, whereas dysregulated gene expression...

RNA Innovation Seminar: Graham Erwin, Stanford University

"Discovering and Targeting Repeat Expansions in Human Disease" Graham Erwin, Ph.D. Stanford Cancer Institute Postdoctoral Fellow Department of Genetics Stanford University     In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Expansion of a single repetitive DNA sequence, termed a tandem repeat (TR), is known to cause more than 50 diseases. However, repeat expansions...

Researchpalooza

Stop by the CRB booth (#1) and the SMART Center (#2) on September 13 at the Researchpalooza event!

RNA Innovation Seminar: Jeffrey Barrick, UT at Austin

"Turning Bugs into Features: Engineering and Evolving Insect Symbiont-Mediated RNA Interference" Jeffrey Barrick, Ph.D. Associate Professor of Molecular Biosciences University of Texas at Austin     In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Many insects have co-evolved associations with microbial symbionts that are more consequential than our relationship with the human microbiome. These...

“Awakenings” Film Screening and Panel Discussion at the Michigan Theater

https://youtu.be/7exeVt7CaE4 "Awakenings" (1990) The victims of an encephalitis epidemic many years ago have been catatonic ever since, but now a new drug offers the prospect of reviving them. Join us for a pre-film panel discussion at 6:00 PM with neurology and neurologic disease physicians and scientists from University of Michigan's Center for RNA Biomedicine: Michelle...

RNA Innovation Seminar: Guizhi (Julian) Zhu, University of Michigan

"Engineer and deliver nucleic acid immunotherapeutics and vaccines – a focus on small circular mRNA (circRNA) vaccines" Guizhi (Julian) Zhu, Ph.D. Ara G. Paul Associate Professor of Pharmaceutical Science University of Michigan   In-person: BSRB, ABC Seminar Rooms / hybrid link Abstract: Our ultimate research goal is to develop clinically translatable nucleic acid therapeutics and...

RNA Innovation Seminar: Susan Gottesman, NIH/NCI

"Bacterial Small RNAs: Regulatory Circuits, On & Off Switches, & Quality Control" Susan Gottesman, Ph.D. Chief, Laboratory of Molecular Biology NIH/NCI Distinguished Investigator     In-person: BSRB, ABC Seminar Rooms / hybrid link Abstract: Bacteria use small regulatory RNAs (sRNAs) and the RNA chaperone Hfq to regulate mRNA translation and stability, akin to miRNAs and...

RNA Innovation Seminar: Irina Artsimovitch, Ohio State University

"Locking Rho up" Irina Artsimovitch, Ph.D. Arts & Sciences Distinguished Professor Department of Microbiology The Ohio State University In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Bacterial termination factor Rho co-transcriptionally surveils the nascent RNA and releases damaged and junk transcripts from RNA polymerase. During rapid growth, Rho maintains the transcriptome health, but how is Rho...

RNA Innovation Seminar: George Lisi, Brown University

"The Invisible Dance of CRISPR-Cas9 through Molecular Space and Time" George Lisi, Ph.D. Thomas J. & Alice M. Tisch Assistant Professor Department of Molecular Biology, Cell Biology & Biochemistry Brown University   In-person: BSRB, ABC seminar rooms / hybrid link Abstract: This talk will focus on long-range signaling in CRISPR-Cas9, a cutting-edge genome editing tool....

RNA Innovation Seminar: Andy Berglund, University at Albany

"Mis-splicing in repeat expansion diseases and development of potential therapeutics" Andy Berglund, Ph.D. Empire Professor of Innovation Director of the RNA Institute University at Albany   In-person: BSRB, ABC Seminar Rooms / hybrid link Abstract: Repeat or microsatellite expansions are responsible for more than 50 human diseases. Myotonic dystrophy (DM), amyotrophic lateral sclerosis (ALS), and...