"Antisense Oligonucleotides for Ataxia" Hayley McLoughlin, Ph.D. Assistant Professor of Neurology Assistant Professor of Human Genetics University of Michigan In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Her talk will cover recent advances in antisense oligonucleotide (ASO) therapy with a particular emphasis towards their mechanistic and therapeutic applications in Ataxia. She will...
"Genetic Variant Effects on Adipose Gene Expression and Their Role in Cardiometabolic Traits." Karen Mohlke, Ph.D. Professor and Associate Chair for Research Oliver Smithies Investigator Department of Genetics, University of North Carolina In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Noncoding genetic variants can affect common diseases and related quantitative traits. Variants may affect...
"Role of Circular RNA in Alzheimer's Disease" Carlos Cruchaga, Ph.D. Director, NeuroGenomics and Informatics Center Washington University in St Louis In-person: BSRB, ABC seminar rooms / hybrid link Short Bio: Dr. Cruchaga is a human genomicist with expertise in multiomics, informatics, and neurodegeneration. He completed his PhD in Biochemistry & Molecular Biology in 2005 at...
"Why Did the RNA Cross the Nanotube? Many questions and (some) answers on tunneling-nanotube medicated RNA transfer between mammalian cells" Gal Haimovich, Ph.D. Assistant Staff Scientist Department of Molecular Genetics Weizmann Institute of Science Virtual only: zoom link Abstract: RNAs have been shown to undergo transfer between mammalian cells, though the mechanism behind this phenomenon...
"A Complicated Family: Conserved & Distinct Functions of tRNA Methyltransferases from Yeast to Humans" Jane Jackman, Ph.D. Professor of Chemistry & Biochemistry Ohio State University In-person: BSRB, ABC seminar rooms / zoom link Abstract: RNA modifications are now known to be a ubiquitous and important feature of cellular RNAs. tRNA are among the most heavily...
"Dancing to a Different Tune: TANGO Provides Hope for Dravet Syndrome" Lori Isom, Ph.D. Chair, Department of Pharmacology Maurice H. Seevers Collegiate Professor of Pharmacology Professor of Molecular and Integrative Physiology Professor of Neurology, University of Michigan Medical School In-person: BSRB, ABC seminar rooms / zoom link Abstract: Dravet syndrome (DS) is a severe developmental...
"Dissect Enhancer Architecture and Map Regulatory Genomic Landscape Across Diverse Cell and Tissue Types Through Nascent Transcriptome Studies" Haiyuan Yu, Ph.D. Tisch University Professor Department of Biological Statistics and Computational Biology Weill Institute for Cell and Molecular Biology Director, Center for Innovative Proteomics (CIP@Cornell) In-person: BSRB, ABC seminar rooms / hybrid link Abstract: Recent studies...
"RNA Synthetic Biology: Towards an Era of RNA Design for Biology & Global Health" Julius B. Lucks, Ph.D. Professor & Associate Chair, Chemical & Biological Engineering Co-Director, Center for Synthetic Biology Northwestern University In-person: BSRB, ABC seminar rooms / hybrid link Abstract: RNAs are emerging as a powerful substrate for engineering cellular behavior. As with...
"Repeat Expansions Instigate Supply Chain Issues in the Nucleus & Cytoplasm" Eric Wang, Ph.D. Associate Professor Molecular Genetics & Microbiology Center for Neurogenetics University of Florida In-person: BSRB, ABC seminar rooms / hybrid link Keywords: Repeat expansions, myotonic dystrophy, RNA biology, RNA splicing, RNA localization, microscopy
"Mapping Novel RNA Regulatory Networks" Lydia Contreras, Ph.D. Professor-Chemical Engineering Interdisciplinary Life Science Graduate Program University of Texas at Austin In-person: BSRB ABC Seminar Rooms / hybrid link Abstract: While advances in omics-based technologies has led to the discovery of hundreds of sRNAs, their identification and characterization has lagged. Even in the model gram-negative...
