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X-WR-CALNAME:Center for RNA Biomedicine
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X-WR-CALDESC:Events for Center for RNA Biomedicine
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DTSTART;TZID=America/Detroit:20230911T160000
DTEND;TZID=America/Detroit:20230911T170000
DTSTAMP:20260418T035809
CREATED:20230801T151536Z
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SUMMARY:RNA Innovation Seminar: Graham Erwin\, Stanford University
DESCRIPTION:“Discovering and Targeting Repeat Expansions in Human Disease”\nGraham Erwin\, Ph.D.\nStanford Cancer Institute Postdoctoral Fellow\nDepartment of Genetics\nStanford University \n  \n  \nIn-person: BSRB\, ABC seminar rooms / hybrid link \nAbstract: Expansion of a single repetitive DNA sequence\, termed a tandem repeat (TR)\, is known to cause more than 50 diseases. However\, repeat expansions are often not explored beyond neurological and neurodegenerative disorders. Here\, I will discuss efforts to identify and target repeat expansions in human disease\, with a focus on neurodegenerative disease and cancer.
URL:https://rna.umich.edu/events/graham-erwin/
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BEGIN:VEVENT
DTSTART;TZID=America/Detroit:20230913T110000
DTEND;TZID=America/Detroit:20230913T140000
DTSTAMP:20260418T035809
CREATED:20230911T195120Z
LAST-MODIFIED:20230911T195351Z
UID:11576-1694602800-1694613600@rna.umich.edu
SUMMARY:Researchpalooza
DESCRIPTION:Stop by the CRB booth (#1) and the SMART Center (#2) on September 13 at the Researchpalooza event!
URL:https://rna.umich.edu/events/researchpalooza/
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DTSTART;TZID=America/Detroit:20230925T160000
DTEND;TZID=America/Detroit:20230925T170000
DTSTAMP:20260418T035809
CREATED:20230801T154411Z
LAST-MODIFIED:20230922T220005Z
UID:11203-1695657600-1695661200@rna.umich.edu
SUMMARY:RNA Innovation Seminar: Jeffrey Barrick\, UT at Austin
DESCRIPTION:“Turning Bugs into Features: Engineering and Evolving Insect Symbiont-Mediated RNA Interference”\nJeffrey Barrick\, Ph.D.\nAssociate Professor of Molecular Biosciences\nUniversity of Texas at Austin \n  \n  \nIn-person: BSRB\, ABC seminar rooms / hybrid link \nAbstract: Many insects have co-evolved associations with microbial symbionts that are more consequential than our relationship with the human microbiome. These symbionts may live within insect cells\, be inherited across generations\, and support host survival. My research group and our collaborators have developed genetic toolkits for engineering diverse bacterial symbionts associated with flies\, aphids\, bees\, and other insects. Because of their important and integrated functions\, engineered symbionts can be used to study insect biology\, protect beneficial insects\, and prevent pests from vectoring disease. Recently\, we have examined how culturable “protosymbiont” strains of Serratia symbiotica colonize aphids and demonstrated that they are transmitted to offspring. We are now attempting to attenuate the pathogenicity of these strains to initiate new stable symbioses. In other work\, we have shown that the honey bee gut symbiont Snodgrassella alvi can be engineered to express double-stranded RNAs that induce a targeted RNA interference response in their hosts. These engineered symbionts can be used to knock down expression of bee genes as a tool for functional genomics. We have also used double-stranded RNA expression by symbionts to prime the bee immune system against viral infection and induce a self-killing response in parasitic Varroa mites that feed on bees in order to protect pollinator health.
URL:https://rna.umich.edu/events/jeffrey-barrick/
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DTSTART;TZID=America/Detroit:20230927T180000
DTEND;TZID=America/Detroit:20230927T210000
DTSTAMP:20260418T035809
CREATED:20230802T145829Z
LAST-MODIFIED:20230822T162119Z
UID:11270-1695837600-1695848400@rna.umich.edu
SUMMARY:"Awakenings" Film Screening and Panel Discussion at the Michigan Theater
DESCRIPTION:“Awakenings” (1990) \nThe victims of an encephalitis epidemic many years ago have been catatonic ever since\, but now a new drug offers the prospect of reviving them.  \nJoin us for a pre-film panel discussion at 6:00 PM with neurology and neurologic disease physicians and scientists from University of Michigan’s Center for RNA Biomedicine: Michelle Hastings\, Ph.D.; Maria G. Castro\, Ph.D.; Christiane Wobus\, Ph.D.; Henry Paulson\, M.D.\, Ph.D.; Peter Todd\, M.D.\, Ph.D.; and moderated by Nils G. Walter\, Ph.D. \n\n\n\nFilm screening will begin at 7:00 PM. The story of a doctor’s extraordinary work in the Sixties with a group of catatonic patients he finds languishing in a Bronx hospital. Speculating that their rigidity may be akin to an extreme form of Parkinsonism\, he seeks permission from his skeptical superiors to treat them with L-dopa\, a drug that was used to treat Parkinson’s disease at the time. From director Penny Marshall and starring Robert De Niro and Robin Williams. \n121 minutes. Drama. PG-13. \n$10.50 General | $8.50 Students\, Seniors\, U.S. Veterans | $8 MTF Members \n\n \n\nPresented with the University of Michigan Center for RNA Biomedicine\, Michigan Medicine and Michigan Theater Foundation
URL:https://rna.umich.edu/events/awakenings-film-screening-and-panel-discussion-at-the-michigan-theatre/
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