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SUMMARY:RNA Innovation Seminar: Laura Scott\, Ph.D.\, University of Michigan School of Public Health
DESCRIPTION:“Regulation of RNA levels in muscle and adipose tissues by sex and genetic variants”\nLaura Scott\, Ph.D.\nResearch Professor\, Biostatistics\nUniversity of Michigan School of Public Health \nResearch interests:\nDr. Scott uses a combination of bulk and single nucleus omic data – RNA expression\, chromatin accessibility\, metabolites and DNA methylation – to understand the cellular genetic regulatory landscape and to infer biological connections between genetic variation and disease risk. \nClick here to read more about Dr. Scott and her work in a 2020 Faculty Spotlight article. \nIn-person: BSRB\, Kahn Auditorium / hybrid link\n \nAbstract:\nGene expression is regulated by multiple factors including genetic variation\, sex\, and cell type. I will describe differences by sex in human skeletal muscle cell type composition\, cell type-level gene expression and chromatin accessibility\, and bulk miRNA expression in 287 people. I will describe regulation of subcutaneous adipose gene expression by genetic variants in a meta-analysis of >2\,200 people. These studies help to better understand transcription and post-transcriptional regulation of gene expression by sex  and genetic regulation of gene expression.
URL:https://rna.umich.edu/events/rna-innovation-seminar-laura-scott-ph-d-university-of-michigan-school-of-public-health/
LOCATION:BSRB – Kahn Auditorium
CATEGORIES:Seminar
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