U-M Data blitz and Posters

2019 Fourth Annual Symposium “Foundational RNA Biosciences: From Discovery to Function” Posters

  • Chengxin Zhang RNA-align: quick and accurate alignment of RNA 3D structures based on size-independent TM-scoreRNA
  • Emily Sherman Discovery and investigation of SART3 as a putative miR-34a–binding protein
  • Haley Amemiya A newly discovered bacterial immune system is essential for coping with viral infections
  • Sarah Hanks Extensive differential gene expression by sex in human skeletal muscle and adipose tissues
  • Shannon Wright Native functions and deleterious effects of RAN translation in unmethylated full mutation Fragile X stem cell-derived neurons.
  • Zhujun Yi Loss of KDM6A Upregulates EMT and Activin Signaling and Promotes Cell Migration/Invasion in Pancreatic Ductal Adenocarcinoma
  • Ashley Kalinski Local translation of dual leucine zipper kinase in axons
  • Kunal Khanna A Novel Single Molecule Microscopy Technique for more Sensitive and Extremely Specific Sensing of miRNAs
  • Ajay Larkin Real-time single-cell visualization of epigenetic inheritance and its dependency on the cell cycle
  • Ahmed Malik Regulation and function of Matrin 3 in ALS/FTD
  • Debra Walter Experimental microRNA target gene discovery and relevance for human disease
  • Meredith Purchal Structure and function of yeast pseudouridine synthase 7
  • Shuang Lu CROSSTALK BETWEEN EPIGENETIC MECHANISM AND TGF-β SIGNALING IN PANCREATIC CANCER
  • Sydney Rosenblum Developing methods for the discovery and validation of pre-miRNA-protein interactions
  • Hannah Foley Structure Determination of pre-microRNA-31 using NMR Spectroscopy
  • Elham Asghari Adib DLK-regulated response to motor neurons axonal injury
  • Adrien Chauvier Co-transcriptional folding of a riboswitch controls the fate of the transcriptional machinery
  • Shuai Hu Identification of novel ROS-signaling genes as potential therapeutic targets for pancreatic cancer using next-generation sequencingand survival analysis
  • Zhonggang Hou Introducing Long-Range Genomic Deletions in Human Cells Using Type I CRISPR-Cas
  • Anoumid Vaziri Metabolic-Epigenetic Regulation of Sweet Taste by Diet
  • Andi Cani Development of a Whole-Urine RNA Next Generation Sequencing-Based Assay for Early Detection of Aggressive Prostate Cancer
  • Sahil Chhabra Machine Learning Helps Recover Atomically Correct RNA-Ligand Poses
  • Mohammed Sayed A NOVA1-PTBP1-PTBP2 Axis Dictates hTERT Alternative Splicing in Neuronal Differentiation and Cancer
  • Indranil Malik RNA toxicity in repeat expansion diseases
  • John Moldovan RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNAs
  • Ishwarya Venkata Narayanan Association between transcription, splicing and RNA turnover processes
  • Karen Montoya Towards a post-PCR world: direct counting of microRNAs from single cells
  • Tyler Smith Decoupling the roles of peptide and mRNA in ribosome pausing during the translation of positively charged peptide sequences
  • Monika Franco mRNA modification can alter translation elongation, fidelity and termination
  • Mehmet Tardu Ribosome profiling of cells lacking the ribosome associated complex component Zuo1
  • Mitsuhiro Nakamura A Single-Strand Nuclease Activity of the LINE-1 ORF2-Encoded Protein
  • Naveen Jasti Probing RNA Secondary Structure within LINE-1 Retrotransposons
  • Karan Bedi Characterization of novel primary miRNA transcription units in human cells using Bru-seq nascent RNA sequencing
  • Megan Trotter Conversion of Random X-inactivation to Imprinted X-inactivation by Maternal PRC2
  • Milan Samanta Induction of X-chromosome Inactivation by the Histone Demethylase SMCX/KDM5C

2018 Third Annual Symposium “Advancing Basic RNA Biosciences into Medicine” Data Blitz Line up

  • Yan Zhang, PhD, Assistant Professor, Biological Chemistry, “Programmable RNA Recognition and Cleavage by N. meningitidis CRISPR-Cas9”
  • Mats Ljungman, PhD, Associate Professor, Radiation Oncology and Environmental Health Sciences and Maria Castro, PhD, R. C. Schneider Collegiate Professor of Neurosurgery, Professor, Cell and Developmental Biology, “Identification of Novel Glioblastoma-associated lncRNAs”
  • Marissa Cloutier, MPH, Graduate Student, Kalantry Lab, “ Differential Roles of Xist RNA vs. Xist DNA in X-chromosome Inactivation”
  • Adrien Chauvier, PhD, Postdoctoral Fellow, Walter Lab, “Co-transcriptional Folding of a Riboswitch Controls the Fate of the Transcriptional Machinery”
  • Sami Barmada, MD, PhD, Angela Dobson Welch and Lyndon Welch Research Professor, Assistant Professor, Neurology, and  Claudia Figueroa-Romero, PhD, Research Investigator, Program for Neurology Research & Discovery, Biological Chemistry, “Abnormal RNA Stability Impacts Ribosomal and Mitochondrial Function in Amyotrophic Lateral Sclerosis”
  • Akira Ono, PhD, Assosiate Professor, Microbiology and Immunology, Medical School, and Sarah Veatch, PhD, Associate Professor of Biophysics and Physics, “Identifying Sites of HIV-1 RNA Translation”

2017 Second Annual Symposium “RNA in Precision Medicine” Data Blitz Line up

  • Jiaqi Shi, MD, PhD, Assistant Professor, Pathology, “A MicroRNA Links TGF-β Signaling Pathway to Histone Modification”
  • Mats Ljungman, PhD, Professor Radiation Oncology “Role of miRNA in cellular reprogramming”
  • Yan Zhang, PhD, Assistant Professor, Biological Chemistry “The Biology and Molecular Mechanism of the Neisseria meningitidis CRISPR-Cas9 Pathway”
  • Laura Scott, PhD, Research Associate Professor, School of Public Health “The genetic regulatory signature of type 2 diabetes in pancreatic islets”
  • Kristin Koutmou, PhD Assistant Professor, Chemistry: “Ribosomes slide on homopolymeric A and U stretches”
  • Peter K Todd, MD, PhD, Neurology, “How RNA repeats elicit unconventional translation of toxic proteins in Amyotrophic Lateral Sclerosis”

2016 Inaugural Symposium “Can RNA Answer It All? From the Origin of Life to the Future of Biomedicine” Data Blitz Line up

  • Scott Barolo, “Cis-regulatory control of gene transcription: decoding the enhancer
  • Claudia Figueroa-Romero, “Tiny yet powerful: microRNAs in ALS pathology”
  • Jim Bardwell, “RNA has Chaperone Activity”
  • Anjan Saha, “Characterizing Centromeric alpha-Satellite RNAs (CeASaRs): An Adventure into Uncharted Territory”
  • Michael Kearse, “Repeat associated non-AUG initiated translation in neurodegenerative disease”
  • Nancy Wu, “Ribonuclease P catalyzed tRNA maturation in human mitochondria”
  • Alice Telesnitsky, “How HIV RNA 5′ end structure illuminates viral RNA fate determination”
  • Stephen Parker, “Enhancer(RNA)opathies in type 2 diabetes”
  • Jayakrishnan Nandakumar, “Silencing of a gene by a noncoding RNA derived from its 3′ UTR”
  • Elizabeth Abshire , “Structural and Functional Studies of a Human 3′ to 5′ RNA Exonuclease Implicated in Obesity.”
  • Sami Barmada, “RNA decay in ALS”
  • Andrzej Wierzbicki, “Superpowers of specialized RNA polymerases”
  • Peter Freddolino, “Mapping and modeling microbial RNA interaction networks”
  • Tony Chun, “SPECtre: a spectral coherence-based classification of actively translated transcripts from ribosome profiling sequence data”
  • Amanda Garner, “High-Throughput Platform Assay Technology for the Discovery of pre-microRNA-Selective Small Molecule Probes”